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In this study, MitoQ was found to enhance hair growth and reverse DHT-induced hair loss in a mouse model of androgenetic alopecia by mediating the WNT/β-catenin pathway and increasing CYP19A1 expression, suggesting potential as a therapeutic intervention.

This study found that topical trypsin application after hair removal in mice led to cell death at the follicular papilla, which delayed hair growth and pigmentation.

In this study, topical trypsin treatment following depilation in a mouse model induced cell death at the follicular papilla, delaying hair growth and pigmentation.

In this study using a mouse model with alopecia areata, the researchers found that ruxolitinib enhances hair regrowth by inhibiting the JAK-STAT signaling pathway, reducing inflammation and oxidative stress, and decreasing apoptosis, which supports its clinical effectiveness in treating this condition.

This study found that stress-related hair loss may be driven by CRH-mediated mechanisms that inhibit autophagy and increase apoptosis in dermal papilla cells, suggesting potential therapeutic targets like PTEN activation or rapamycin to enhance autophagy.

In this study using mouse models, researchers found that stress-related hair loss may occur due to CRH-induced PTEN loss and inhibition of autophagy via the PI3K/AKT/mTOR pathway in dermal papilla cells, suggesting potential treatments through PTEN activation or autophagy enhancement.

In this study, researchers found that dermal papilla cell exosomes can enhance hair follicle stem cell proliferation and reduce apoptosis through the Wnt3a/β-catenin signaling pathway, offering insights for potential hair problem treatments.

This study defines classification criteria for hair follicle dystrophy using a mouse model of chemotherapy-induced alopecia, providing tools for standardized hair damage assessment.

In a study on the effects of stromal vascular fraction (SVF) and platelet-rich plasma (PRP) on hair growth in nude mice, researchers found that both treatments promoted hair growth, with SVF showing a stronger effect.

This study suggests that the MAPK/ERK signaling pathway plays a role in the regulation of cell proliferation, apoptosis, and cycling in rat urethral plate fibroblasts affected by finasteride-induced hypospadias.

This study found that exosomal miR-181a-5p promotes hair follicle growth and development in vitro by activating the Wnt/β-catenin signaling pathway and suppressing hair follicle stem cell apoptosis.

This study found distinct gene expression patterns in the blood of alopecia areata patients, suggesting involvement of immune processes and new pathways like Wnt signaling and apoptosis in disease pathogenesis.

This review discusses the therapeutic mechanisms of Traditional Chinese Medicine in treating alopecia but reports no new clinical results; the authors emphasize the need for more guided clinical application and research on herbal combinations.

This study found that Cyanidin-3-O-glucoside and Vitisin A were able to penetrate mouse skin and improve issues related to hair follicle miniaturization and apoptosis in androgenetic alopecia, suggesting these compounds as potential alternative treatments for hair loss.

This review discusses the advancements in intraoperative stem cell therapies and highlights their potential to improve hair regrowth, but it reports no new clinical results.

In this study, researchers found that during zebrafish telencephalon regeneration, the lesioned hemisphere showed distinct gene expression changes and activated Wnt/β-catenin signaling early after injury, suggesting this pathway's significant role in recovery.

In this study, minoxidil and human platelet lysate affected gene expression related to hair growth signaling pathways in mouse hair follicle cells.

This study found that human placental extract promoted hair growth and influenced cellular pathways in vitro and rat models, suggesting potential for future hair loss treatments.

This study found that in vitro, EGCG may help treat colorectal cancer by targeting iron chelation and the ER stress pathway, leading to apoptosis in cancer cells while sparing normal cells.

In this study on testosterone-induced benign prostatic hyperplasia in rats, hydroxychloroquine significantly reduced prostate-related markers and enhanced therapeutic effects when combined with finasteride, suggesting potential as a new treatment approach.

This study found that psychoemotional stress disrupts hair growth in mice by terminating anagen and suggests a potential pathway for pharmacological management of stress-related hair loss in humans.

This study found that taurine significantly mitigated DHT-induced androgenetic alopecia in male C57BL/6 mice by promoting hair regrowth, enhancing hair follicle cycle progression, reducing apoptosis, and downregulating key androgen-related signaling pathways, highlighting its potential as a therapeutic candidate for hair loss management.

In this study, neutralizing nerve growth factor reduced stress-triggered hair loss in mice, suggesting that nerve-immune system interactions and neurogenic inflammation contribute to this condition.

This study identified changes in transcription factor gene expression across various signaling pathways during inner ear hair cell regeneration in birds, revealing patterns and potential new pathways for future investigation.

This review explores the mechanisms of hair cell death due to factors like noise, ototoxic drugs, and aging and reports no conclusive clinical results; ongoing research may eventually enable preventive treatments for hearing loss.

This review examines the life cycle, biomarkers, and functions of hair follicle stem cells, emphasizing their role in hair loss therapy and other skin and hair disorders, but reports no new clinical results.

This study found that the medicinal formula YH0618 may reduce toxicity from the chemotherapy drug doxorubicin, improving side effects like hair loss and organ damage, while maintaining its anti-cancer effects.

This article explores the potential of combining biomarkers to assess and improve treatments for chemotherapy-induced alopecia, highlighting the limited availability of data on hair follicle damage markers with and without scalp cooling.

This review compiles epidemiological data on actinic keratoses and suggests promoting strategies like early diagnosis and photoprotection to prevent progression to skin cancer, but it reports no new clinical findings.

This study concluded that early-stage tissue-engineered skin substitutes, developed using skin progenitor cells, had a better graft efficiency and supported hair follicle formation, which may improve wound healing outcomes.