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Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Wnt1/βcatenin signaling is crucial for heart repair after injury.

Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Telogen effluvium is a reversible hair loss condition that requires a detailed diagnosis and often resolves on its own.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

PGD2 stops hair growth and is higher in bald men with AGA.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Special fiber materials boost the healing properties of certain stem cells.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.

New effective scar treatments are urgently needed due to the current options' limited success.