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The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Most low-level light therapy studies did not accurately report how light was measured, affecting treatment reliability.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Testosterone therapy can help improve sexual desire and function in postmenopausal women but may cause side effects and is not FDA-approved for this use.

Special immune cells called Tregs can help prevent lung scarring by blocking a specific growth factor.

Bergamot may improve heart health, skin conditions, and mood, but more research is needed to confirm these benefits.

Prolactin may affect hair growth differently based on gender and scalp area.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Cell-based therapies using dermal papilla cells and adipocyte lineage cells show potential for hair regeneration.

The study suggests that being overweight or obese, not PCOS itself, is strongly linked to insulin resistance.

The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.

Diagnosing PCOS in teenagers is hard because its symptoms often look like normal puberty, and there's a need for better diagnosis methods and agreement on criteria.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

Women with PCOS have unhealthy changes in their cholesterol particles that are not related to their body weight.

Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.

Cheonggukjang may help prevent and manage various diseases and improve overall health, but its odor and safety concerns need addressing.

Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

Balding people may have higher heart disease risk.

Cyclodextrins improve finasteride's solubility and bioavailability for hair loss treatment.

New treatments for hair loss may target specific pathways and generate new hair follicles.

Adipose-derived stem cells show promise in treating skin conditions like vitiligo, alopecia, and nonhealing wounds.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

Mild essential fatty acid deficiency can cause health issues and is worsened by low-fat diets.

Stem cells can help regenerate hair follicles.

Patients with oral lichen planus or oral lichenoid reactions had worse cholesterol levels and a higher risk of obesity compared to healthy individuals.