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This review emphasizes the potential of repurposing topical L-thyroxine for skin ulcers and telogen effluvium and highlights the need for further exploration of its use in dermatology.

The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.

This review explores herbal medications for skin disorders, covering their clinical efficacy, safety, and common drug interactions, but reports no new clinical results.

The researchers observed that normal murine hair follicles are direct targets for melatonin, with receptor expression varying throughout the hair cycle, suggesting melatonin's role in hair cycle control.

This review discusses the use of topical and intralesional corticosteroids for treating alopecia areata, highlighting their efficacy and safety but noting recurrence and pain as limitations; no new clinical results are reported.

This study found that telogen effluvium, a type of hair loss, was prevalent among 24% of COVID-19 patients, likely triggered by stress and medication related to the illness.

This review discusses the development of the MATH+ treatment protocol for COVID-19 patients, detailing its scientific and clinical rationale, but reports no new experimental findings.

This review discusses the role of extracellular vesicles from specific skin cells in wound healing, emphasizing their potential in regenerative medicine and reporting no new experimental results.

This study suggests that the rs2075876 variant in the AIRE gene may significantly increase susceptibility to alopecia areata in the examined male population.

In this study, researchers found that androgenetic alopecia is associated with increased gene expression related to inflammation, stress, and fibrosis, particularly affecting the hair follicle stem cells and showing similarities to diseases like psoriasis.

This article reviews the role of keratins in epithelial function and structure, discussing their involvement in growth control, organelle functions, and pathomechanisms of disorders, but reports no new clinical results.

This review discusses the role of skin enzymes in drug metabolism and emphasizes the need for models assessing enzyme activity to evaluate the safety and bioequivalence of topical generic drugs, highlighting efforts to standardize testing protocols for transdermal products.

This study found that epidermal-specific deletion of integrin α3β1 significantly reduces papilloma formation in a skin carcinogenesis model by modulating HB stem cell behavior and CCN2 expression.

This paper highlights the growing scientific interest in plant extracts for cosmetics due to their potential benefits, including antioxidant, antimicrobial, and protective properties, while emphasizing the need for quality and safety assessment to mitigate possible adverse reactions.

This review discusses the role of multiomics in understanding skin repair and regeneration mechanisms and reports no new results; the authors suggest it may lead to personalized medicine advancements and improved treatments.

This study suggests that targeting olfactory receptors in the lung epithelium might help treat odorant-induced asthma in cases without type 2 inflammation, as these receptors could play a role in airway sensitivity to smells.

In this study, researchers reported that compounds from Bruguiera gymnorhiza leaves showed anti-inflammatory potential in in silico analyses, with favorable drug properties and specific binding to the IKKβ receptor, suggesting possible development into anti-inflammatory drugs.

In this narrative review, researchers outlined the role of T cells in the autoimmune pathogenesis of alopecia areata and highlighted ongoing research into therapeutic pathways, beyond current JAK inhibitors, aimed at developing new treatments for the disease.

This study found that specialized nipple epidermis in mice is maintained by the repression of TGFβ signaling through estrogen, which highlights the role of hormonal regulation in epidermal maintenance.

This review discusses the roles of glucocorticoid and sex hormone receptors in the skin and their clinical importance, but reports no new research findings.

This study found that flower extracts of Wedelia trilobata may serve as a promising active ingredient for cosmeceutical products due to their antioxidant, anti-inflammatory, and antimicrobial properties.

This case report found that a novel botanical treatment halted disease progression and promoted hair regrowth in four patients with lichen planopilaris, indicating potential for use as a safe alternative therapy.

This study found that exposing adult esophageal epithelial cells to skin stroma can induce them to transition toward a hair follicle identity, with HIF1a playing a crucial role in this conversion process.

This review discusses the formation and structure of the cornified cell envelope in the epidermis, highlighting biochemical pathways and genetic factors, but presents no new experimental results.

This study suggests that inducible transgenic mice showing hair follicle changes similar to telogen effluvium in humans might serve as a useful model for understanding this type of hair loss.

Hair increases in size when it absorbs water, and treatments like bleaching affect how much water it can take in.

This study suggests a potential role for S100A7 and IL-17 in the pathogenesis of lichen planopilaris.

This study found that sebaceous glands in the skin are primarily renewed by their own stem cells during normal conditions, but after injury, they regenerate through stem cells from hair follicles, highlighting stem cell plasticity and regeneration capabilities.

In this case series, four African American women with treatment-resistant central centrifugal cicatricial alopecia showed scalp itch relief and significant hair regrowth after using a new botanical formula for 8 weeks to 1 year, with no adverse effects reported.

This study concluded that the Wnt signaling pathway does not significantly influence human keratoacanthoma development, but the overexpression of Sox9 suggests alternate signaling involvement.