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The skin is vital for protection, temperature control, fluid balance, immunity, and sensing, with damage affecting daily life and mental health.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Exosomal miRNAs from stem cells can help improve skin health and delay aging.

The document outlines steps for moving fat from one body part to another.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.

Tissue stiffness affects hair follicle regeneration, and Twist1 is a key regulator.

Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.

Lowering testosterone speeds up wound healing in male mice.

Growing human skin cells in a 3D environment can stimulate new hair growth.

Cathepsin L is essential for normal hair growth and development.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

The document concludes that using stem cells to regenerate hair follicles could be a promising treatment for hair loss, but there are still challenges to overcome before it can be used clinically.

Baby teeth stem cells can potentially grow organs and treat diseases.

Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Hair loss can indicate underlying systemic diseases and addressing these can sometimes reverse the hair loss.

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

Eicosanoids are crucial for skin health, and targeting their pathways may help treat skin conditions.

Certain genes in Iranian sheep are linked to wool production and heat adaptation.

Vitamin A helps skin stem cells decide their function, aiding in hair growth and wound repair.

Rat dermal papilla cells have unique genes crucial for hair growth.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Melanocytes are important for skin and hair color and protect the skin from UV damage.

Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.