13 citations,
June 2017 in “Biochimie open” All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.
2 citations,
January 2023 in “Plants” Plant bioactive compounds are important for health and can help prevent various diseases.
2 citations,
October 2018 in “Physiology & behavior” Early changes in brain chemicals affect how a drug reduces alcohol intake in rats.
1 citations,
November 2021 in “Biomolecules & Therapeutics” Activating δ-opioid receptors can help hair grow.
1 citations,
September 2021 in “European Journal of Inflammation” 1 citations,
March 2018 in “F1000Research” Diabetic neuropathy in mice is linked to poor mitochondria function and lower brain hormone production.
January 2022 in “International Journal of Medical Sciences” Cedrol may be an effective treatment for colorectal cancer.
September 2021 in “Journal of skin and stem cell” Lactium, a milk protein, can help reduce symptoms of skin disorders linked to stress and anxiety without side effects.
January 2016 in “Medicinski Podmladak”
205 citations,
September 2018 in “Nutrients” Essential oils from Curcuma species, like turmeric, have compounds that can fight inflammation, cancer, and bacteria, and can also stimulate hair regrowth in bald males.
44 citations,
November 2012 in “Endocrine Practice” We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.
21 citations,
March 2018 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” 5-alpha-reductase inhibitors may help stabilize or slow down hair loss in some frontal fibrosing alopecia patients, but more research is needed to confirm their effectiveness and safety.
15 citations,
June 2008 in “Headache” People with migraines often have mental health conditions, and treatment should be personalized to address both issues safely.
11 citations,
November 2021 in “International journal of molecular sciences” Gut microbes significantly affect brain steroid levels.
11 citations,
November 2018 in “International Journal of Trichology”
10 citations,
July 2022 in “Dermatology and Therapy” Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.
9 citations,
January 2023 in “Phytomedicine” More high-quality research is needed to recommend flavonoids and saponins for clinical use.
8 citations,
May 2019 in “International Journal of Trichology” 5 citations,
May 2019 in “Neuroscience letters” Hormones during puberty increase certain receptors in the brain, and this change is influenced by estrogen levels.
4 citations,
April 2017 in “F1000Research” Mitochondrial problems in diabetic nerve damage might cause pain by lowering the production of certain nerve-related steroids.
2 citations,
May 2023 in “International Journal of Molecular Sciences” The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.
2 citations,
November 2022 in “Frontiers in Pharmacology” Local healers in Addis Ababa use 81 medicinal plants, mainly from the Asteraceae family, to treat skin and general diseases, with Echinops kebericho being an endangered plant important in their practices.
1 citations,
June 2022 in “Frontiers in Neuroanatomy”
February 2024 in “Scientific Reports” Cinnamic acid may help hair grow by activating oxytocin receptors.
December 2023 in “F&S reports” PCOS may increase the risk of mental health issues like depression and anxiety.
November 2023 in “Frontiers in Neuroendocrinology” Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.
September 2023 in “Journal of Nutrition and Metabolism” One Ashwagandha extract may help protect cells with its antioxidant properties, while another could promote hair growth.
August 2023 in “Stem cell reviews and reports”
June 2023 in “Journal of Education, Health and Sport” CBD is effective for certain epilepsy conditions, shows promise for other health issues, but needs more research for safety and effectiveness.
May 2023 in “Endocrine, metabolic & immune disorders” Hibiscus rosa-sinensis is used in traditional medicine and is safe in high doses, with various health benefits.