February 2021 in “PDEAS International Journal of Research in Ayurved and Allied Sciences” This article reviews Ayurvedic concepts and treatments related to hair and reports no new clinical results.
October 2018 in “Ayurlog: national journal of research in ayurveda science” This article discusses methods to enhance scalp hair strength and beauty according to Ayurvedic principles, without presenting new clinical results, and emphasizes understanding various aspects of hair health from Ayurvedic texts.
August 2023 in “International journal of research in Ayurveda and pharmacy” This analysis explored Ayurveda's approach to addressing hair fall, emphasizing the use of herbs and lifestyle modifications for prevention and regrowth, and critically examined classical Ayurvedic concepts related to causation and treatment of hair loss.
September 2024 in “International Journal of Pharmaceutical Quality Assurance” This review suggests that Shirodhara, an ancient Ayurvedic therapy, may significantly improve mental well-being by reducing post-COVID anxiety, depression, and insomnia, although further randomized controlled trials are needed to confirm these promising findings.
2 citations
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December 2023 in “Journal of Ayurveda and Integrated Medical Sciences” In this case study, a 16-year-old boy with alopecia areata experienced complete hair regrowth after 4 months of Ayurvedic treatments, including Shamana Chikitsa and Raktamokshna, with no adverse effects reported.
135 citations
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December 2015 in “Expert Opinion on Biological Therapy” This review synthesizes recent research on exosomes, highlighting their role as key modulators in regenerative outcomes and suggesting they may offer advantages over stem cell-based therapies in process and regulation.
29 citations
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December 2017 in “Molecular therapy” This study found that enzyme replacement therapy in mice with a severe form of classical homocystinuria improved metabolic patterns and alleviated many clinical symptoms.
26 citations
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June 2018 in “The journal of immunology/The Journal of immunology” This study demonstrated that AIRE-deficient rats exhibit key symptoms of APECED, making them a relevant model for exploring potential treatments.
1 citations
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January 2020 This study found that Ift20 is essential for hair follicle stem cell identity and hair regrowth, and it regulates keratinocyte migration during wound healing through focal adhesion integrin recycling, independently of ciliogenesis.
October 2025 in “Editora Pasteur eBooks” The abstract discusses the multidisciplinary nature and advancement of dermatology and aesthetic procedures within the health sciences, emphasizing the integration of diagnostic, corrective, preventive, and therapeutic approaches, but does not provide specific study results.
January 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, the researchers found that deleting ceramide synthase 4 in the skin's epidermis alters stem cell differentiation, disrupting hair follicle structure and barrier function, potentially leading to immune responses similar to atopic dermatitis.
June 2024 in “International Journal of Research in Ayurveda and Pharmacy” This study explores Ayurvedic concepts for hair conditions such as hair loss, premature greying, alopecia areata, seborrheic dermatitis, and dandruff, highlighting treatments that include Panchakarma and Rasayana medicines for potential relief.
July 2023 in “Journal of ayurveda and integrated medical sciences” This case report details the treatment of a 28-year-old woman with PCOS symptoms, including irregular menstruation, weight gain, and hair loss, using Ayurvedic management after ultrasound showed a bilateral PCO pattern.
January 2022 in “International journal of Ayurveda and pharma research” This review discusses the Ayurvedic perspective on premature graying of hair (Akala Palitam) and reports no new clinical results, emphasizing the need for understanding its etio-pathogenesis for effective management.
7 citations
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January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that thymus transplantation in athymic mice resulted in T-cell-driven hair follicle depigmentation and loss, without multiorgan autoimmune disease, highlighting mechanisms of tissue-specific tolerance.
November 2024 in “Jurnal Biomedika dan Kesehatan” This study explores premature graying of hair, outlining potential causes such as genetic factors, nutritional deficiencies, and autoimmune disorders, and evaluates various management strategies including nutritional supplements, pharmacotherapy, and addressing underlying conditions.
January 2026 in “Journal of Ayurveda Case Reports” In this study, a 21-year-old male with alopecia areata showed complete hair regrowth after following a 100-day holistic Ayurveda treatment, which included Pracchana karma, Gunja-Kalihari lepa application, and Ayurveda formulations, resulting in a SALT-2 score reduction from 66% to 0%.
July 2025 in “Journal of Ayurveda and Integrated Medical Sciences” This study examines the traditional Ayurvedic practice of Nasya Karma, highlighting its potential benefits for skin texture, hair growth, and facial rejuvenation through nasal administration, by exploring its anatomical and current applications in cosmetology.
July 2025 in “Journal of Integrated Health Sciences” In this study, a 32-year-old female with alopecia areata experienced significant symptom relief after receiving traditional Ayurvedic treatments, including Virechana, Pracchana, and Rasayana therapies, alongside external application of Chakramarda. The protocol was reported to be simple, cost-effective, and highly efficacious.
October 2023 in “Journal of Indian System of Medicine” This study discusses how Ayurveda approaches the management of premature hair greying differently than contemporary science, emphasizing lifestyle regimens, rejuvenation practices, and the use of herbal drugs rooted in Ayurveda pharmacodynamics.
128 citations
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August 2020 in “Cell stem cell” In this study, researchers found that extrafollicular progenitors marked by Hic1 are the main contributors to reparative fibroblasts in wound repair, with potential to modulate healing outcomes through genetic and pharmacological interventions.
20 citations
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January 2022 in “REVIEWS ON ADVANCED MATERIALS SCIENCE” This review explores how nanoparticles enhance cosmeceutical formulations, analyzing their roles in transporting active ingredients, and highlights the progress and challenges in using nanotechnology for beauty and health products.
4 citations
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January 2025 in “The Journal of Cell Biology” This study found that deleting ceramide synthase 4 in skin epidermis stem cells disrupts hair follicle and skin barrier function, leading to immune responses similar to atopic dermatitis, due to imbalances in lipid composition affecting differentiation.
1 citations
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May 2023 in “European Journal of Human Genetics” This study observed that numerical chromosomal aberrations were more common in men with severe male factor infertility and azoospermia compared to those with other sperm quality issues, while chromosomal translocations were significantly associated with oligoasthenozoospermia, highlighting important genetic counseling considerations.
July 2026 in “Antioxidants” This review identifies agri-food by-products as promising sources of antioxidant compounds for cosmeceutical applications, examining their potential for skin, oral, and hair care, while noting the need for further research on safety and clinical efficacy.
June 2025 in “Clinical Cosmetic and Investigational Dermatology” This study examined the factors contributing to gray hair, such as genetics and lifestyle, and found that while graying correlates with some health conditions, it is primarily a physiological process rather than a pathological one.
40 citations
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August 2018 in “Skin appendage disorders” This review examines complementary and alternative medicine for alopecia and finds limited support from robust clinical trials, highlighting the need for standardized studies to evaluate efficacy and safety.
121 citations
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May 2009 in “Journal of Ethnopharmacology” This study found that the methanol extract of Eclipta alba showed dose-dependent hair growth promoting activity in pigmented C57/BL6 mice by influencing the transition from the telogen to anagen phase.
76 citations
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August 2018 in “International Journal of Cosmetic Science” This review discusses the use of Dermal Papilla cells as in vitro models for studying hair growth modulators, emphasizing their role in aiding the development of new hair treatments, but reports no new clinical results.
13 citations
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August 2018 in “Clinical Chemistry” This study determined that a total testosterone concentration of ≥5.1 nmol/L identified androgen-producing tumors in women with severe hyperandrogenemia, while a lower threshold of ≥2.2 nmol/L was found for diagnosing pathologic hyperandrogenism in postmenopausal women.