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    Glossary Antiviral

    Antivirals are a class of medications designed to treat viral infections by inhibiting the development and replication of viruses. While primarily used for conditions like influenza or HIV, certain antivirals have been studied for their potential effects on hair loss, particularly in cases where viral infections may contribute to conditions like telogen effluvium or alopecia areata. Key distinguishing characteristics of antivirals include their mechanism of action, which targets specific stages of the viral life cycle, and their varying effectiveness depending on the type of virus and the individual’s response to treatment.

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    1. Evaluation of anti-Zika virus activities of broad-spectrum antivirals and NIH clinical collection compounds using a cell-based, high-throughput screen assay Antiviral research · 2017 · 111 citations
    2. Cepharanthine: a review of the antiviral potential of a Japanese-approved alopecia drug in COVID-19 Pharmacological Reports · 2020 · 70 citations
    3. Antiviral and Anti-Inflammatory Plant-Derived Bioactive Compounds and Their Potential Use in the Treatment of COVID-19-Related Pathologies Journal of Xenobiotics · 2022 · 26 citations
    4. Antiviral Drugs Screening for Swine Acute Diarrhea Syndrome Coronavirus International Journal of Molecular Sciences · 2022 · 13 citations
    5. Antiviral effects of human placenta hydrolysate (Laennec®) against SARS-CoV-2 in vitro and in the ferret model The Journal of Microbiology · 2021 · 13 citations
    6. Cepharanthine: A review of the antiviral potential of a Japanese-approved alopecia drug in COVID-19 2020 · 4 citations
    7. Antiviral drugs prolong survival in murine recessive dystrophic epidermolysis bullosa EMBO molecular medicine · 2024
    8. Review article: dermatological complications of immunosuppressive and anti-TNF therapy in inflammatory bowel disease Alimentary Pharmacology & Therapeutics · 2013 · 60 citations
    9. Spironolactone: An Anti-androgenic and Anti-hypertensive Drug That May Provide Protection Against the Novel Coronavirus (SARS-CoV-2) Induced Acute Respiratory Distress Syndrome (ARDS) in COVID-19 Frontiers in Medicine · 2020 · 36 citations
    10. Down-RANKing the Threat of HSV-1: RANKL Upregulates MHC-Class-I-Restricted Anti-Viral Immunity in Herpes Simplex Virus Infection Journal of Investigative Dermatology · 2015 · 2 citations
    11. Anti-Alopecia Activity of Alkaloids Group from Noni Fruit against Dihydrotestosterone-Induced Male Rabbits and Its Molecular Mechanism: In Vivo and In Silico Studies Pharmaceuticals · 2022 · 1 citations
    12. The antiviral activity of a small molecule drug targeting the NSP1-ribosome complex against Omicron, especially in elderly patients Frontiers in Cellular and Infection Microbiology · 2023 · 6 citations
    13. NATURAL ANTIVIRALS FOR THE MANAGEMENT OF SARS-COVID-19: A REVIEW International Journal of Research in Ayurveda and Pharmacy · 2021
    14. An update of anti-viral treatment of COVID-19 Turkish Journal of Medical Sciences · 2021 · 51 citations
    15. A Reappraisal of the Antiviral Properties of and Immune Regulation through Dietary Phytochemicals ACS Pharmacology & Translational Science · 2023 · 11 citations
    16. DEVELOPING NEW DUAL-ACTION ANTIVIRAL/ANTI-INFLAMMATORY SMALL MOLECULES FOR COVID-19 TREATMENT USING IN SILICO AND IN-VITRO APPROACHES 2024
    17. Cutaneous Adverse Events in Patients with Chronic Hepatitis C during Treatment with Directly Acting Antiviral Agents: A cohort study The Egyptian Journal of Hospital Medicine · 2024
    18. Host-Directed FDA-Approved Drugs with Antiviral Activity against SARS-CoV-2 Identified by Hierarchical In Silico/In Vitro Screening Methods Pharmaceuticals · 2021 · 42 citations
    19. Evaluating the Metabolomic Profile and Anti-Pathogenic Properties of Cannabis Species Metabolites · 2024 · 9 citations
    20. The Advances of Broad-Spectrum and Hot Anti-Coronavirus Drugs Microorganisms · 2022 · 9 citations
    21. Host-directed FDA-approved drugs with antiviral activity against SARS-CoV-2 identified by hierarchical <i>in silico/in vitro</i> screening methods bioRxiv (Cold Spring Harbor Laboratory) · 2020
    22. 5α-Reductase inhibitors, antiviral and anti-tumor activities of some steroidal cyanopyridinone derivatives International Journal of Biological Macromolecules · 2011 · 26 citations
    23. Bioactivity and In Silico Studies of Isoquinoline and Related Alkaloids as Promising Antiviral Agents: An Insight Biomolecules · 2022 · 21 citations
    24. The brief overview, antivirus and anti-SARS-CoV-2 activity, quantitative methods, and pharmacokinetics of cepharanthine: a potential small-molecule drug against COVID-19 Frontiers in Pharmacology · 2023 · 8 citations
    25. The Need for Speed and Efficiency: A Brief Review of Small Molecule Antivirals for COVID-19 Frontiers in drug discovery · 2022 · 6 citations
    26. Comparison of viral RNA–host protein interactomes across pathogenic RNA viruses informs rapid antiviral drug discovery for SARS-CoV-2 Cell Research · 2021 · 100 citations
    27. Development of Provesicular Nanodelivery System of Curcumin as a Safe and Effective Antiviral Agent: Statistical Optimization, In Vitro Characterization, and Antiviral Effectiveness Molecules · 2020 · 37 citations
    28. LC-ESI-QTOF-MS/MS Analysis, Cytotoxic, Antiviral, Antioxidant, and Enzyme Inhibitory Properties of Four Extracts of Geranium pyrenaicum Burm. f.: A Good Gift from the Natural Treasure International Journal of Molecular Sciences · 2021 · 53 citations
    29. A microscopy-based small molecule screen in primary neurons reveals neuroprotective properties of the FDA-approved anti-viral drug Elvitegravir Molecular Brain · 2020 · 3 citations
    30. Epidermal γδ T cells, CD8 T cells and macrophages are increased in number in alopecia areata and express BST2 as part of an interferon-driven antiviral gene signature bioRxiv (Cold Spring Harbor Laboratory) · 2025