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Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

Targeting FGFR-1 with antisense oligonucleotides may help treat baldness by increasing hair follicle activity.

Topical oligonucleotide therapy targets hair follicles effectively.

New topical treatment using spherical nucleic acids shows promise in reducing psoriasis inflammation.

Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.

Adding a second method to PROTACs could improve cancer treatment.

Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.

New partnerships, clinical trials, and drug approvals marked progress in therapeutic delivery in July 2018.

Type 2 diabetes in youth is increasing, with high treatment failure rates and more severe than Type 1; certain drugs can lower lipid levels effectively with varying side effects, and apples may benefit heart health like statins but with fewer side effects.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Polymeric nanoparticles show promise for treating skin diseases.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Probiotic bacteria improved skin and hair health in aged mice.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.

Natural gene therapy shows promise for treating skin disorders like epidermolysis bullosa.

Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.

Zebrafish larvae are used to study and find treatments for ear cell damage because they are easier to observe and test than mammals.