3 citations
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June 2023 in “Journal of cosmetic dermatology” This study found that a topical cream containing CBD and EPA reduced signs of extrinsic skin aging, including wrinkle volume and skin elasticity, in clinical and laboratory settings.
October 2024 in “Internal Medicine” In this case report, a 47-year-old man experienced systemic hair loss after starting hemodialysis, which resolved after discontinuing the antipruritic drug nalfurafine, suggesting its role in causing hair follicle capillary regression.
4 citations
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February 2017 in “Journal of Cutaneous Medicine and Surgery” This study assessed the dermatologic potential of western red cedar, white spruce, birch, balsam poplar, and black spruce used in First Nations medicine, highlighting several active compounds relevant to dermatology, but noted a lack of high-quality evidence in existing research.
4 citations
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September 2014 in “Elsevier eBooks” This review discusses the safety of dermatological medications used during pregnancy, highlighting that retinoids have strong teratogenic risks and should be used with caution; it reports no new clinical results.
3 citations
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October 2021 in “International Journal of Research in Ayurveda and Pharmacy” This study reviewed the pharmacological properties of Priyaladi lepa, an Ayurvedic formulation, and reported its potential anti-dandruff benefits due to anti-inflammatory, anti-fungal, anti-microbial, anti-pruritic, antioxidant, and exfoliation effects, warranting further research for managing Darunaka (dandruff).
July 2024 in “Medical alphabet” The authors concluded that "burning scalp" syndrome lacks general treatment recommendations, but therapeutic cosmetics showing antipruritic and anti-inflammatory effects may offer promise for long-term management and prevention.
July 2017 in “International journal of Ayurvedic and herbal medicine” This study revealed that Madayantika siddha taila, containing sesame oil, showed effectiveness in treating Darunaka (seborrhea capitis) by addressing aggravated Vata and Kapha doshas.
December 2019 in “Pubvet” This article discusses the diagnosis and management of allergic dermatoses in dogs, focusing on clinical diagnosis, complementary tests, and various treatment strategies, but it reports no new results.
August 2025 in “Biomolecules” This review discusses the potential topical benefits of cannabidiol in dermatology and cosmetics, highlighting its diverse effects and therapeutic roles but reports no new clinical results, emphasizing the need for further research.
42 citations
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November 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This review discusses recent advancements in hair cosmetic agents, including topical growth stimulants and anti-aging compounds, emphasizing molecular technology's role in understanding hair growth and aging; it does not report new results.
May 2026 in “Applied Sciences” In this review, the authors reported that sprout extracts, rich in bioactive compounds, show promising effects on skin health, such as enhancing collagen synthesis, improving hydration, and reducing inflammation, though most evidence comes from laboratory and animal studies.
1 citations
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March 2023 in “Phytochemistry Reviews” This review discusses the potential of CBD for treating skin disorders, the challenges of its topical administration, and current strategies to improve its application, but reports no new clinical findings.
1 citations
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November 2025 in “Journal of Cosmetic Dermatology” This source reports on ongoing clinical trials examining the therapeutic potential of topical CBD for skin conditions like acne, dermatitis, and psoriasis, and emphasizes that upcoming trial results will be crucial in evaluating its effectiveness.
191 citations
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February 2002 in “Archives of Dermatology” This review discusses herbal therapies for dermatologic disorders, focusing on those with scientific evidence of efficacy and common interactions, but reports no new clinical results.
4 citations
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January 2011 in “International Journal of Trichology” This case series reported that patients with trichotillomania and pseudofolliculitis experienced improvement in itch symptoms and hair regrowth after receiving topical steroids, topical, or oral antibiotics.
9 citations
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June 2017 in “Pharmacological Reports” This study found that ATP-sensitive potassium channels may play a role in chloroquine-induced itching in mice, as channel openers reduced scratching behavior while a blocker reversed these effects.
June 2026 in “Immunity Inflammation and Disease” In this study, researchers observed that dandruff involves altered keratinocyte activity and a low-grade inflammatory response characterized by increased interleukin-17-producing T-cells and CCL17 levels, but without significant changes in immune cell populations or skin barrier lipids.
July 2024 in “Research Square (Research Square)” In this study, ATP-sensitive potassium channel openers, diazoxide and minoxidil, reduced scratching in cholestatic mice, suggesting these channels may play a role in cholestatic itch, while the channel blocker glibenclamide increased scratching behavior.
September 2013 in “The veterinary nurse” This article discusses the management of pruritic skin diseases in cats, focusing on diagnosis and the importance of client communication, but reports no new clinical results.
July 2018 in “Elsevier eBooks” This review discusses various causes and treatments of scalp pruritus, distinguishing between conditions with primary skin lesions and those without, but provides no new clinical results.
September 2025 in “PubMed” In this study, auricular electrostimulation effectively relieved dextran-induced pruritus in mice, comparable to loratadine treatment, and is attributed to down-regulating the H1R/TRPV1 signaling pathway and reducing inflammatory cells in the skin.
48 citations
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January 2020 in “Cochrane Database of Systematic Reviews” This study found that serlopitant may reduce pruritus intensity compared to placebo in patients with chronic pruritus of unknown origin, though evidence is of low certainty and effects on other outcomes are unclear.
This study used data mining of the FDA Adverse Event Reporting System to analyze drug-induced pruritus, revealing differences in gender, age, and weight among cases, and identified ophthalmic drugs and systemic antibacterials as common triggers, contributing to potential prevention and treatment strategies for pruritus.
5 citations
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December 2015 in “Dermatologic Therapy” In this study, topical phenylephrine significantly reduced hair shedding and increased the force needed to pluck hair in women undergoing cosmetic procedures, suggesting its potential utility for traction alopecia.
1 citations
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July 2024 in “JAAD Case Reports” This study links scalp pruritus in lichen planopilaris and its variants to the inflammation-induced release of substance P and calcitonin gene-related peptide by sensory nerves around hair follicle inflammation sites.
April 2016 in “Journal of Investigative Dermatology” This study found that topical phenylephrine, an α1-AR agonist, significantly reduced hair shedding and increased epilation force threshold in women experiencing traction alopecia during cosmetic procedures.
April 2023 in “IntechOpen eBooks” This review discusses neuropathic pruritus, detailing its clinical presentations and management strategies, but reports no new clinical results.
September 2023 in “Journal of the American Academy of Dermatology” This study found that in participants with notalgia paresthetica, 8 weeks of treatment with difelikefalin significantly improved itch intensity and increased the rate of strict complete response compared to placebo, starting as early as week 3.
September 2012 in “The Thai journal of veterinary medicine” In this case study, apitoxin aquapuncture combined with herbal medicine was reported to have a favorable therapeutic effect in treating canine superficial pyoderma.
This article reviews the complex causes of scalp pruritus and emphasizes the importance of thorough diagnosis, though some cases may lack a clear cause and rely on empirical treatment to alleviate symptoms.