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The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Finasteride effectively treats baldness but may cause sexual side effects.

Fat cells in the skin help start healing and form important repair cells after injury.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Platelet-rich plasma might help with hair growth and skin conditions, but more research is needed to prove its effectiveness and safety.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

New topical antifungals and delivery systems are improving treatment for fungal skin infections, but patient education and prevention are key.

Folliculitis decalvans is a rare scalp condition causing scarring hair loss, treated with long-term antibiotics and other medications, but it often comes back and is hard to manage.

Liposomes could improve how skin care products work but are costly and not very stable.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Foals with Rhodococcus equi infection often have other health problems that lower their chances of survival.

PRP injections improve hair thickness for baldness.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

Smoking may contribute to hair loss in men.

Fullerenes show potential in skin care but need more safety research.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.