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Intestinal intraepithelial lymphocytes are crucial for gut immunity and maintaining the mucosal barrier.

The nail matrix has a reduced immune response, protecting it from autoimmunity.

Creating fully functional artificial skin for chronic wounds is still very challenging.

Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.

Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.

Macroalgae compounds offer sustainable, effective benefits for cosmetics.

Probiotics show promise for health benefits but need more research to understand how they work.

Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.

Hormones and signaling pathways control sebaceous gland function and could help treat acne.

Indian herbal medicine shows promise for treating skin diseases but needs more research to prove effectiveness.

New therapies are being developed that target integrin pathways to treat various diseases.

Future hair cosmetics will be safer and more effective.

Microneedle technology has advanced for painless drug delivery and sensitive detection but faces a gap between experimental use and clinical needs.

MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.

Healthy scalp reduces hair loss by managing oxidative stress.

Staphylococcus epidermidis A/C strains are more antibiotic-resistant and infection-adapted, while B strains thrive in hair follicles.

Children with darker skin tones can have specific skin conditions that need tailored treatments.

The hydrogel speeds up burn wound healing and promotes tissue regeneration.

Vitamin D receptor is important for regulating hair growth and wound healing in mice.

Thiazole, a sulfur and nitrogen chemical, is useful in creating potential drugs for conditions like seizures, cancer, bacterial infections, tuberculosis, inflammation, malaria, viruses, Alzheimer's, diabetes, and A1-receptor issues.

Some drugs may help treat both COVID-19 and radiation injury.

Menopause causes dry skin, wrinkles, and hair changes, with hormone therapy helping but not recommended just for these issues.

Inorganic-based biomaterials can quickly stop bleeding and help wounds heal, but they may cause issues like sharp ion release and pH changes.

Plant-based products can improve hair and skin health without harmful side effects.

Eleven traditional Polynesian plants show potential for natural anti-aging, hair growth, and skin brightening products.

Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.

Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

New materials that better mimic natural skin structure could improve healing, especially for chronic wounds.

Coconut seed extract may effectively treat scabies in rabbits by killing mites and reducing inflammation.

More high-quality research is needed to recommend flavonoids and saponins for clinical use.