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New treatments for male hypogonadism are effective and should be personalized.

Lifestyle changes and medical treatments can help manage infertility in women with PCOS.

This article reviews the potential of combining antiandrogenic and antiestrogenic treatments for BPH, highlighting aromatase inhibitors, but presents no new clinical results; further research is needed.

In this report, five female patients undergoing hormonal anticancer therapy for breast cancer prevention developed pattern alopecia, which the authors attribute to androgen-estrogen imbalance caused by antiestrogenic drugs.

This paper reviews the diagnostic criteria, etiological factors, and treatment approaches for PCOS, highlighting the importance of considering metabolic issues such as insulin resistance and obesity, but reports no new findings.

This study describes the enzymatic processes through which DHEA is converted to active sex steroids in human skin, highlighting an androgenic effect on sebaceous glands and estrogenic effects in the vagina.

This case report describes total alopecia in a 53-year-old woman after 13 months of tamoxifen treatment for breast cancer, with normal hair distribution maintained elsewhere.

Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.

In this study, treatment with DHEA induced mild to moderate hyperplasia of sebaceous glands in ovariectomized rats, which was prevented by the antiandrogen Flutamide but not by the antiestrogen EM-800.

This study examines the pathogenetic role of hormonal imbalances in chronic prostatitis, highlighting that decreased androgens and increased estrogens contribute to prostate inflammation and impaired spermatogenesis, and explores hormonal therapies' potential for restoring reproductive function.

Some breast cancer treatments caused long-term hair loss in women, similar to a condition called alopecia areata.

This study found that A-ring reduced derivatives of norethisterone and levonorgestrel exhibit estrogen-like potency in rat osteoblasts, suggesting a mechanism for 19-norprogestins' bone restoration effects in postmenopausal women.

This study reports that scalp cooling therapies and minoxidil may promote hair regrowth in patients experiencing persistent chemotherapy-induced alopecia, with trichoscopy aiding in treatment assessment.

This review discusses various prostate cancer prevention strategies and reports no new clinical results; the authors highlight the need for ongoing research in this area.

This chapter reviews pharmacodynamic evaluations in endocrine disorders focusing on oral antidiabetics, insulin analogues, and hormone interactions, but reports no new results.

Hormonal contraceptives and related compounds can increase health risks like thrombosis and affect sexual function.

This study found that four new progesterone derivatives reduced prostate weight in gonadectomized hamsters, suggesting potent in vivo antiandrogenic effects similar to finasteride.

This review discusses the 2011 publications on the side effects of sex hormones and related compounds, without reporting new clinical results.

This study observed that new trienone compounds consistently showed higher 5alpha-reductase inhibitory activity compared to corresponding dienones across various biological models.

This study found that two new progesterone derivatives showed higher antiandrogenic effects and 5α-reductase inhibition than finasteride in hamsters, particularly reducing seminal vesicle weight and flank organ size.

This study suggests that adding androgens to menopausal hormone therapy may reduce breast cancer risk by counteracting estrogen-driven proliferation in postmenopausal breast tissue.

This review examines the effects of antiandrogens on female reproductive systems, particularly regarding environmental endocrine disruptors, and presents no new research findings.

This research outlines that antiandrogens have mechanisms involving competitive inhibition of androgen binding and enzyme inhibition, with contraindications during pregnancy due to potential fetal risks.

This review discusses various sex hormones and related compounds, including estrogens and anabolic steroids, but reports no new findings; it highlights existing literature from 2014 regarding their use and effects.

This study found that specific steroids, particularly 5 and 7b, decreased growth of prostate and seminal vesicles and bound to the androgen receptor, showing comparable pharmacological activity to finasteride.

This review discusses the potential antiandrogenic effects of environmental chemicals on reproductive development, highlighting concerns about their impacts on humans but reports no new clinical findings.

This article discusses the complexities of androgen and antiandrogen therapies in women, detailing diagnostic measures, the effects on libido, and the potential benefits of new progestins with antiandrogenic properties, but presents no new empirical findings.