1 citations,
December 2022 in “Biomolecules & therapeutics” Minoxidil may help reduce aging effects in brain cells.
1 citations,
January 2018 in “Recent clinical techniques, results, and research in wounds” Using developmental signaling pathways could improve adult wound healing by mimicking scarless embryonic healing.
1 citations,
January 2001 in “Journal of Toxicology-cutaneous and Ocular Toxicology” Hair follicles could be used to deliver drugs effectively, with the right understanding and methods.
April 2024 in “Military Medical Research/Military medical research” Cellular and immunotherapies show promise for healing chronic wounds but need more research.
March 2024 in “Medical lasers” Multiple-wavelength radiation helps hair grow by boosting early hair follicle development.
135 citations,
December 2006 in “PLoS Medicine” Hyaluronate fragments can help reverse skin thinning by working with the CD44 receptor.
116 citations,
September 2020 in “Nature Communications” The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.
33 citations,
April 2020 in “Journal of Clinical Investigation” Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.
2 citations,
January 2023 in “Pharmaceuticals” Sex and sex hormones can affect brain inflammation in Parkinson's disease, with male mice being more affected and female mice showing a protective effect.
50 citations,
March 2021 in “Journal of investigational allergology & clinical immunology” Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.
2 citations,
December 2016 in “Experimental cell research” The research found a way to identify and study skin cells with stem cell traits, revealing they behave differently in culture and questioning current stemness assessment methods.
1 citations,
July 2023 in “Nature communications” MOF controls key genes for skin development by regulating mitochondrial and ciliary functions.
1 citations,
January 2012 in “International journal of trichology” Sheep hair follicle cells can grow a lot but need the dermal papilla to do so.
131 citations,
March 2004 in “The American journal of pathology” Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.
55 citations,
June 2014 in “Nature Communications” Tcf3 helps cells move and heal wounds by controlling lipocalin 2.
16 citations,
October 2019 in “Biological & Pharmaceutical Bulletin” Houttuynia cordata extract may help hair grow by improving cell survival and increasing cell growth.
4 citations,
June 2013 in “The Journal of Rheumatology” The document concludes that various findings in rheumatology offer insights into disease severity, treatment responses, and potential risks in medication, with some limitations due to unspecified participant numbers.
August 2018 in “Journal of Investigative Dermatology” Centrosomes are essential for healthy skin and hair growth, and their role is different from that of cilia.
252 citations,
January 2008 in “Trends in Endocrinology and Metabolism” Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.
180 citations,
January 2003 in “American Journal of Clinical Dermatology” Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.
161 citations,
August 2013 in “Journal of experimental botany” Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.
100 citations,
September 1999 in “British Journal of Dermatology” The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.
87 citations,
July 2018 in “Biochimica et Biophysica Acta (BBA) - Molecular Cell Research” Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.
81 citations,
November 2012 in “Journal of the National Cancer Institute” The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.
64 citations,
March 2005 in “Journal of Investigative Dermatology” Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.
58 citations,
February 2016 in “Scientific reports” Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.
57 citations,
March 2013 in “Journal of Dermatological Science” Improving the environment and cell interactions is key for creating human hair in the lab.
56 citations,
January 2015 in “Circulation” Finasteride helps reduce heart issues and improves heart function.
53 citations,
September 2020 in “Stem Cell Research & Therapy” New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.
38 citations,
June 2018 in “Archives of Toxicology” Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.