November 1990 in “Inpharma weekly” Flutamide effectively treated hair growth and related symptoms in women, with common side effects like dry skin and hot flushes.
82 citations,
February 1989 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.
5 citations,
January 1984 in “Journal of psychosomatic obstetrics and gynecology/Journal of psychosomatic obstetrics and gynaecology” The treatment reduced hair growth and testosterone in women with excess hair and had some effects on stress responses.
November 2024 in “Clinical Cosmetic and Investigational Dermatology” Rosemary oil may effectively treat hair loss with fewer side effects, but more research is needed.
January 2018 in “Elsevier eBooks” The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.
June 2019 in “The Egyptian Journal of Fertility and Sterility” Chromium picolinate was better tolerated than metformin for PCOS with fewer side effects.
1 citations,
June 2012 in “Springer eBooks” Acupuncture may improve reproductive and metabolic functions in PCOS without negative side effects, but more research is needed to confirm its effectiveness.
11 citations,
January 2016 in “Bipolar Disorder” Valproate is a mood stabilizer for bipolar disorder but has side effects and risks, especially during pregnancy.
109 citations,
November 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Targeting hair follicles can improve skin treatments and reduce side effects.
4 citations,
October 2007 in “Dermatologic Clinics” Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.
January 2010 in “Springer eBooks” Hirsutism can lower a woman's quality of life, causing emotional distress and affecting social and work opportunities.
15 citations,
April 2020 in “Journal of The American Academy of Dermatology” Spironolactone effectively treats female pattern hair loss with few side effects.
November 2020 in “Elsevier eBooks” Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.
18 citations,
January 2001 in “Annual Reports in Medicinal Chemistry” Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.
124 citations,
July 2012 in “Archives of Dermatological Research” Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.
94 citations,
January 2000 in “The Journal of Clinical Endocrinology and Metabolism” Spironolactone most effective for hirsutism, but has side effects.
78 citations,
January 2000 in “Gynecological Endocrinology” Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.
11 citations,
January 2001 in “Cambridge University Press eBooks” Androgens can cause hair growth in some areas but hair loss on the scalp.
43 citations,
May 1986 in “Clinics in Endocrinology and Metabolism” Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.
11 citations,
January 1998 in “Dermatology” Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.
9 citations,
March 2001 in “Clinics in dermatology” Hirsutism in women is often due to hormone sensitivity and has significant psychological effects.
10 citations,
December 2017 in “Chemosphere” Bisphenol-A (BPA) increases connections between brain cells and boosts their activity, but it blocks the effects of a male hormone on brain cell plasticity.
1 citations,
July 1997 in “Inpharma Weekly” Finasteride improves hair growth and satisfaction in men with male pattern baldness but may cause sexual side effects.
January 2012 in “The Year book of dermatology” Finasteride 5mg/day improves hair loss in normoandrogenic Asian women.
January 2017 in “Indian journal of drugs in dermatology” Saw palmetto extract may help with hair loss and acne but needs more research on safety and long-term effects.
26 citations,
December 1981 in “British journal of dermatology/British journal of dermatology, Supplement” Cyproterone acetate reduced hair growth in most hirsute females and made hair softer, thinner, and lighter.
30 citations,
October 2020 in “Nature Communications” Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
20 citations,
July 2009 in “Journal of Pediatric and Adolescent Gynecology” Quick treatment of hair disorders in teenage girls is important because of the emotional effects.
6 citations,
March 2019 in “International Journal of Molecular Medicine” Finasteride microspheres help reduce hair loss for up to eight weeks with fewer side effects.
September 1998 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” The document concludes that individualized treatments for hair issues are effective, certain hair changes can indicate neurocutaneous diseases, specific lotions improve skin health, laser hair removal works but needs more study on long-term effects, men's cosmetics are diverse, peeling is effective but can have side effects, and facial pigmentation is often due to overactive skin cells.