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Topical rosuvastatin and melatonin creams significantly reduce psoriasis severity and are safe.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Some alternative therapies for vitiligo show promise but need more research.

Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.

The MPV/PC ratio can help assess disease activity in alopecia areata.

Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Probiotics show promise for health benefits but need more research to understand how they work.

TLR3 signaling enhances the immunosuppressive properties of human periodontal ligament stem cells.

Up to half of people experience itchy scalp, often due to skin conditions like seborrheic dermatitis or psoriasis, and treatments vary based on the specific cause.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Methotrexate is effective for treating rheumatoid arthritis but requires regular monitoring.

Metabolic syndrome's individual issues are real and need treatment to reduce diabetes and heart disease risks.

Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.

Nonantibiotic macrolides show promise for treating various inflammatory skin conditions.

Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.

PEGL-DOX causes Hand-Foot Syndrome due to skin reactions from prolonged circulation and ROS generation.

taVNS reduces vitiligo symptoms in mice.

The document concludes that diagnosing and treating Human African Trypanosomiasis is challenging, but new treatments like fexinidazole are promising.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

SLE and DM can coexist but are rare and need careful evaluation.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Single-cell engineered biotherapeutics show promise for skin treatment but need more research and trials.

Procyanidin compounds from apples and barley promote hair growth and prevent hair cell death.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Minoxidil and finasteride effectively treat hair loss.