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AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

The mtDNA N haplogroup is linked to a higher risk of late-onset lupus and specific symptoms in Han Chinese women.

New topical treatment using spherical nucleic acids shows promise in reducing psoriasis inflammation.

Acankoreoside J from Acanthopanax koreanum may help promote hair growth.

IL-33 is linked to hair follicle damage in psoriasis and could be a treatment target for hair loss in this condition.

Drug repositioning offers hope for new, affordable treatments for a genetic skin disorder called ARCI.

An imbalance in gut bacteria is linked to skin immune diseases and may affect their outcomes and related health issues.

Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.

Cell therapy shows promise for treating severe psoriasis but needs more research to confirm safety and effectiveness.

Plasmacytoid dendritic cells are a key factor in causing hair loss in alopecia areata and could help differentiate it from other hair loss conditions.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

Using a fractional laser can stimulate hair growth, but the intensity and duration of inflammation are crucial. Too much can cause ulcers and scarring. Lower beam energy and fewer treatments are recommended to avoid damage.

Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.

Patients with RASopathies have a higher risk of autoimmune disorders and should be routinely screened.

Most patients experienced mild to moderate skin problems during a trial for a desmoid tumor treatment.

Diabetes can cause a variety of skin disorders, some of which may signal more serious health issues.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Tofacitinib temporarily regrew hair in a man with alopecia, but its effects didn't last.

A substance from hair follicle stem cells helps heal skin wounds in diabetic mice by promoting cell growth and preventing cell death.

A new non-invasive method can analyze skin mRNA to understand skin diseases better.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

A substance called poly(I:C) increases a protein called carbonic anhydrase II in skin cells, which might help with skin defense and healing.

Exosomes from stem cells help hair regrowth by activating a specific signaling pathway.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

The conclusion is that analyzing RNA from skin oils is a promising way to understand skin diseases.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Activating the Nrf2 pathway reduces inflammation and cell activation in human hair follicles, suggesting a potential treatment for certain hair loss conditions.

New drugs for Alzheimer's and rheumatoid arthritis advanced, a Zika vaccine is in development, and there were business deals in anesthesia and oncology.