research Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine
The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.
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research Advanced Inhibition of Undesired Human Hair Growth by PPARγ Modulation
GMG-43AC may help reduce unwanted hair growth and treat certain hair loss conditions.
research Beneficial Effects of Astragaloside IV for Hair Loss via Inhibition of Fas/FasL-Mediated Apoptotic Signaling
Astragaloside IV may help prevent hair loss by blocking a specific pathway that leads to cell death.
research Cepharanthine: A Review of the Antiviral Potential of a Japanese-Approved Alopecia Drug in COVID-19
Cepharanthine, a Japanese hair loss drug, shows promise as a COVID-19 treatment but needs more testing.
research The Cutaneous Side Effects of Selective BRAF Inhibitors and Anti-CTLA4 Agents: The Growing Role of the Dermatologist in the Management of Patients with Metastatic Melanoma
Dermatologists are crucial for managing skin side effects in metastatic melanoma patients using vemurafenib and ipilimumab.
research Hair, Cutaneous Homeostasis, and Stem Cell Functions
Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.
research Janus Kinase Inhibitors Versus Other Biological Treatments in Alopecia Areata
Janus kinase inhibitors show promise in treating alopecia areata but need more safety research.
research New Biomarkers to Evaluate Hyperandrogenemic Women and Hypogonadal Men
The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.
research Low-Dose Naltrexone: A Novel Adjunctive Treatment in Symptomatic Alopecias?
Low-dose naltrexone might be a cheap and effective additional treatment for hair loss with scalp discomfort due to its anti-inflammatory effects and few side effects.
research Use of H-1 Antihistamine in Dermatology: More Than Itch and Urticaria Control: A Systematic Review
H-1 antihistamines may help with various skin conditions, but more research is needed to confirm their effectiveness.
research The Effect of Topical Gel Secretome Hypoxic Mesenchymal Stem Cells on IL-6 and TGF-β Gene Expression in Male Wistar Alopecia-Like Rat Models Induced by Fluconazole
SH-MSCs gel reduced IL-6 and increased TGF-β, suggesting it could treat alopecia.
research Stress and Psychoneuroimmunologic Factors in Dermatology
Stress and emotional factors can worsen skin conditions by affecting the immune system.
research Effect of Topical Gel Administration of Secretome Hypoxia Mesenchymal Stem Cells on IL-10 and TNF-α Gene Expression: An In Vivo Experimental Study in Male Wistar Rats with Fluconazole-Induced Alopecia
SH-MSCs gel can effectively treat alopecia by increasing IL-10 and decreasing TNF-α gene expression.
research Sebum Free Fatty Acids Enhance the Innate Immune Defense of Human Sebocytes by Upregulating Beta-Defensin-2 Expression
Free fatty acids in sebum boost skin's defense against acne by increasing antimicrobial peptides.
research The Application Prospects of Honokiol in Dermatology
Honokiol from Magnolia plants may be beneficial for treating various skin conditions and promoting hair growth.
research Effects of the Complex of Panicum Miliaceum Extract and Triticum Aestivum Extract on Hair Condition
Millet and wheat extracts may improve hair health and promote growth.
research The Inflammatory Aspect of Male and Female Pattern Hair Loss
Inflammation affects hair loss; anti-inflammatory treatments may help.
research Azathioprine-Induced Liver Injury in a Patient with Multiple Autoimmune Syndrome
A man with multiple autoimmune diseases developed liver injury from azathioprine, but his liver improved after stopping the drug.
research Restoration of Hair Growth in Mice with an Alopecia Areata-Like Disease Using Topical Anthralin
Topical anthralin helped regrow hair in mice with a condition similar to human alopecia.
research Co-Editors' Messages
Inflammation linked to the immune response may play a role in causing various types of hair loss.
research Pinus Thunbergii Bark Extract Rich in Flavonoids Promotes Hair Growth in Dorsal Skin by Regulating Inflammatory Cytokines and Increasing Growth Factors in Mice
Pine bark extract helps mice grow hair by reducing inflammation and boosting growth factors.
research Effects of Non-Ablative Fractional Erbium Glass Laser Treatment on Gene Regulation in Human Three-Dimensional Skin Models
Erbium glass laser treatment may help with skin remodeling, reduce inflammation, and improve skin cell maturation.
research Tacrolimus in Dermatology
Tacrolimus is effective for various skin conditions with fewer side effects than cyclosporine.
research Tumor Necrosis Factor in Sepsis
Topical eye β-blockers might cause hair loss, which usually gets better after stopping the medication.
research Rosemary and Neem: An Insight into Their Combined Anti-Dandruff and Anti-Hair Loss Efficacy
Rosemary and neem extract may be an effective natural treatment for dandruff and hair loss.
research Pregnancy and Skin: Changes and Dermatoses
Most skin changes during pregnancy are harmless and temporary, but some can risk the fetus and need careful treatment.
research Recent Therapeutic Developments for Acne
New acne treatments include combination creams, advanced retinoids, and light therapies, focusing on safety and patient adherence.
research The Effects of Narrowbands of Visible Light Upon Some Skin Disorders: A Review
Visible light can improve skin disorders and hair loss, but more research is needed to understand long-term effects.
research Present and Future Use of Exosomes in Dermatology
Exosomes could be key in treating skin conditions and healing wounds.
research Cutaneous Lupus Erythematosus: Overview and Treatment
The document concludes that Cutaneous Lupus Erythematosus has different forms, is influenced by genetic and environmental factors, and can be treated with various medications, but more targeted therapies are needed.