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Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

Testosterone therapy can modestly improve sexual function in menopausal women but should be used cautiously and is not recommended for routine measurement in sexual dysfunction or hirsutism.

Testosterone may slow down wound healing and increase inflammation.

Higher dihydrotestosterone may be linked to more inflammation in COVID-19 patients with low testosterone.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Hair follicles could be used to deliver drugs effectively, with the right understanding and methods.

Oral contraceptives lower testosterone levels in women, especially those with certain genetic traits, and may be linked to increased breast cancer risk.

Dr. Mario Lacouture recommends preventive and specific treatments for skin side effects caused by EGFR inhibitors to improve patients' quality of life.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Some common medications can harm male fertility, but many effects can be reversed.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

People with polycystic ovary syndrome have a higher chance of having chronic thyroiditis.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Some medications can cause acne, and stopping these drugs is the main treatment.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

Red deer only have androgen receptors in neck hair cells for mane growth during breeding season.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.

Antibody treatments show promise for hair loss but need more research.

Targeted therapies for lung cancer are effective but require careful management of side effects to benefit patients.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

New acne treatments show promise as alternatives to traditional therapies.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Statins may help treat PCOS by lowering androgen levels and improving cholesterol.

Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.