research Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One
Adding a second method to PROTACs could improve cancer treatment.
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research Third World Congress of the International Academy of Cosmetic Dermatology
The Third World Congress of the International Academy of Cosmetic Dermatology discussed various topics like hair disorders, skin conditions, wound healing, shampoo technology, acne treatment, and the use of lasers in dermatology.
research Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition
The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.
research N-Terminal Functional Domain of Gasdermin A3 Regulates Mitochondrial Homeostasis via Mitochondrial Targeting
Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.
research A Review on Steroidal 5α-Reductase Inhibitors for Treatment of Benign Prostatic Hyperplasia
New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.
research Identification of Key Genes Induced by Platelet-Rich Plasma in Human Dermal Papilla Cells Using Bioinformatics Methods
Platelet-rich plasma may help hair follicle cells grow by affecting certain genes and pathways.
research Clinical Case of Alopecia Totalis in Pediatric Practice
An 11-year-old child with total hair loss may have a genetic autoimmune disease, and the outlook for hair regrowth is not good.
research Abstracts
New treatments and diagnostic methods for various animal skin conditions showed promising results.
research In-Silico Studies in Herbal Drugs: A Review
Computational methods can speed up and improve the development and safety of herbal drugs.
research Patent Reports
New patents include innovations in skin and hair care, disease treatment, plant stress tolerance, and protein purification.
research Treatment of Androgenetic Alopecia with Sabal Serrulata and Biomimetic Peptides Delivered via Microneedling
Sabal serrulata and biomimetic peptides with microneedling reduced hair loss and improved hair thickness in men with balding.
research Enzymes
Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.
research Fresh Umbilical Cord Blood as a Source of Multipotent Stem Cells: Collection, Banking, Cryopreservation, and Ethical Concerns
Umbilical cord blood is a valuable source of stem cells for medical treatments, but its use is less common than other transplants, and there are ethical issues to consider.
research Nuclear Factor I-C Promotes Proliferation and Differentiation of Apical Papilla-Derived Human Stem Cells In Vitro
NFIC helps human dental stem cells grow and become tooth-like cells.
research A WWP2–PTEN–KLF5 Signaling Axis Regulates Odontoblast Differentiation and Dentinogenesis in Mice
WWP2 is crucial for tooth development in mice.
research Anti-TNF Antibody-Induced Psoriasiform Skin Lesions in Patients with Inflammatory Bowel Disease Are Characterised by Interferon-γ-Expressing Th1 Cells and IL-17A/IL-22-Expressing Th17 Cells and Respond to Anti-IL-12/IL-23 Antibody Treatment
Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.
research The Prevalence of Polycystic Ovary Syndrome in a Normal Population According to the Rotterdam Criteria Versus Revised Criteria Including Anti-Mullerian Hormone
Adding anti-Müllerian hormone to PCOS criteria lowers the number of women diagnosed.
research Anti-Cancer Properties of Olive Oil Secoiridoid Phenols: A Systematic Review of In Vivo Studies
Olive oil compounds may help prevent cancer in animals, but human results are mixed.
research Spearmint Herbal Tea Has Significant Anti-Androgen Effects in Polycystic Ovarian Syndrome: A Randomized Controlled Trial
Spearmint tea may reduce testosterone and self-reported hair growth in women with PCOS.
research Psoriatic Alopecia/Alopecia Areata–Like Reactions Secondary to Anti–Tumor Necrosis Factor-α Therapy: A Novel Cause of Noncicatricial Alopecia
Anti-TNF therapy can cause a unique type of hair loss that may get better with topical treatments without stopping the therapy.
research The Transcriptional Co-Activator cAMP Response Element-Binding Protein-Binding Protein Is Expressed in Prostate Cancer and Enhances Androgen- and Anti-Androgen-Induced Androgen Receptor Function
A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.
research Anti-Androgenicity of Flutamide and Its Metabolite SCH 16423
Flutamide and its metabolite can effectively reduce androgen effects.
research Lifestyle Intervention and Anti-Obesity Therapies in Polycystic Ovary Syndrome: Impact on Metabolism and Fertility
Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.
research Anti-Androgenic Activities of Ganoderma Lucidum
Ganoderma lucidum, a type of mushroom, may help treat enlarged prostate by blocking testosterone conversion.
research Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne
Anti-acne medications may work by reducing the activity of a protein involved in acne development.
research Anti-Androgenic Activities of the Triterpenoids Fraction of Ganoderma Lucidum
The triterpenoids from Ganoderma lucidum can block testosterone effects and may help treat enlarged prostate.
research Anti-Inflammatory, Cyclooxygenase Inhibitory, and Antioxidant Activities of Standardized Extracts of Tridax Procumbens L.
Extracts from Tridax procumbens L. have strong anti-inflammatory and antioxidant effects and block inflammation-causing enzymes.
research Review Article: Dermatological Complications of Immunosuppressive and Anti-TNF Therapy in Inflammatory Bowel Disease
Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.
research Silk-Inspired In Situ Hydrogel with Enhanced Anti-Tumor Immunity for Photodynamic Therapy in Melanoma and Infected Wound Healing
The silk fibroin-based hydrogel shows promise for treating melanoma and healing infected wounds by killing tumor cells and bacteria, and supporting skin recovery.
research Anti-Androgenic Activity of Myricae Cortex: Isolation of Active Constituents from Bark of Myrica Rubra
The bark of Myrica rubra contains compounds that can block testosterone effects and might help prevent hair loss.