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The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Noggin is necessary to start the hair growth phase in skin after birth.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Blocking JAK-STAT signaling can lead to hair growth.

Superficial granulomatous pyoderma is a unique, mild form of skin disease that often heals without strong medication and responds well to milder treatments.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Oxidative stress contributes to hair graying and loss as we age.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Liposomes could improve how skin care products work but are costly and not very stable.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

No treatment fully prevents hair loss from chemotherapy yet.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.

Follistatin helps hair growth and cycling, while activin prevents it.

Mice without the Sept4/ARTS gene heal wounds better due to more stem cells that don't die easily.

The conclusion is that hair growth can be improved by activating hair cycles, changing the surrounding environment, healing wounds to create new hair follicles, and using stem cell technology.

Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

People with alopecia areata often have lower levels of vitamin D, zinc, and folate, but more research is needed to understand if supplements can help treat it.

Children with atopic dermatitis often have sleep problems due to itching and may benefit from melatonin, which helps with sleep and skin symptoms.

Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

Hydrogels could lead to better treatments for wound healing without scars.