research Type-2 Immunity Associated With Type-1 Related Skin Inflammatory Diseases: Friend Or Foe?
Type-2 immunity may influence skin diseases and could be targeted for treatment.
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research Novel Inhibitors of 5α-Reductase
New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.
research Kin-Cohort Analysis of LRRK2-G2019S Penetrance in Parkinson's Disease
The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.
research Xenobiotics In Vitro: The Influence of L-Cystine, Pantothenate, and Miliacin on Metabolic and Proliferative Capacity of Keratinocytes
L-cystine, D-pantothenat, and miliacin together significantly boost keratinocyte growth and metabolism.
research White Lupin Cluster Root Acclimation to Phosphorus Deficiency and Root Hair Development Involve Unique Glycerophosphodiester Phosphodiesterases
White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.
research The Chemokine SDF-1/CXCL12 Regulates the Migration of Melanocyte Progenitors in Mouse Hair Follicles
SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.
research Non-FDA-Approved Uses of Apremilast in Dermatology: A Review of Current Available Literature
Apremilast shows promise for several skin conditions but needs more research.
research Resident Memory T Cells in Autoimmune Skin Diseases
Certain immune cells contribute to skin autoimmune diseases, and some treatments can reverse hair loss in these conditions.
research Neuropsychiatric Lupus: A Severe Manifestation of Systemic Lupus Erythematosus
Neuropsychiatric lupus is a severe form of lupus that needs strong treatment to improve life quality.
research Off-Label Uses of Retinoids in Dermatology
Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.
research Family Planning 2011: Better Use of Existing Methods, New Strategies, and More Informed Choices for Female Contraception
The conclusion is that there is a high demand for new contraceptives that provide both pregnancy prevention and protection against STIs, along with additional health benefits.
research Beta-Caryophyllene Enhances Wound Healing Through Multiple Routes
Beta-caryophyllene helps improve wound healing in mice, especially in females.
research Characterization of CD4+ Stem Cells of the Skin and Their Role in Skin Homeostasis and Tumorigenesis
CD4+ skin cells may be precursors to basal cell carcinoma.
research Chemical Composition and Industrial Applications of Maritime Pine (Pinus Pinaster Ait.) Bark and Other Non-Wood Parts
Maritime pine bark has various chemical components useful for different industrial uses.
research Alpha-1 Adrenergic Receptor Agonist Induced Piloerection Protects Against the Development of Traction Alopecia
Phenylephrine may help prevent hair loss from pulling on the hair roots.
research Automated Machine Learning Analysis of Patients With Chronic Skin Disease Using a Medical Smartphone App: Retrospective Study
Machine learning can predict symptoms and quality of life in chronic skin disease patients using smartphone app data, and shows that app use varies with patient characteristics.
research Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One
Adding a second method to PROTACs could improve cancer treatment.
research Pathogenesis of Alopecia Areata and Vitiligo: Commonalities and Differences
Alopecia areata and vitiligo share immune system dysfunction but differ in specific immune responses and affected areas.
research Polycystic Ovary Syndrome: Current Evidence and Practical Recommendations
The document concludes that more research is needed to include new treatments in guidelines for Polycystic Ovary Syndrome (PCOS).
research Distinct Transcriptional Profiles of the Female, Male, and Finasteride-Induced Feminized Male Anogenital Region in Rat Fetuses
Finasteride exposure affects gene expression and anogenital distance in male rat fetuses.
research Gata6 Promotes Hair Follicle Progenitor Cell Renewal by Genome Maintenance During Proliferation
Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.
research A 57-Year-Old Male Retired Colonel with Acute Ankle Swelling
The retired colonel's ankle swelling was caused by a reaction to the antibiotic levofloxacin.
research Antibacterial And Antifungal Activity Of Hedyotis Corymbosa, Inula Racemose, Holostemma Adakodien Medicinal Plants
The essential oils from Hedyotis corymbosa, Inula racemose, and Holostemma adakodien have significant antibacterial and antifungal properties.
research Celery Ameliorating Against Neurobehavioral and Neurochemical Disorders of Perinatal Lipopolysaccharides Exposure in Mice Offspring
Celery helps protect against developmental and brain issues in mice exposed to certain toxins.
research Synthesis and Actions of 5α-Reduced Metabolites of Testosterone in the Nervous System
Testosterone and its metabolites affect brain functions and could help treat neurological disorders.
research Sex Differences in the Effect of Finasteride on Acute Ethanol Withdrawal Severity in C57BL/6J and DBA/2J Mice
Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.
research Keratin Function and Regulation in Tissue Homeostasis and Pathogenesis
Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.
research Generation of Trichogenic Adipose-Derived Stem Cells by Expression of Three Factors
Scientists made stem cells that can grow hair by adding three specific factors to them.
research An Overview of Animal Models Induced by Glucocorticoids
Glucocorticoids can cause various health issues, but some treatments may help reduce these effects.
research Leflunomide: An Unlikely Trigger and Mechanistically a Beneficial Drug for Alopecia Areata
Leflunomide is more likely to help treat alopecia areata than cause it.