May 2025 in “Scientific Reports” This study found that geraniol, derived from Apiaceae plants, may be an effective and eco-friendly treatment for scabies, achieving complete clinical recovery in infected rabbits within two weeks.
May 2025 in “Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology” In this study, researchers developed "Akaro Spectra," an antiparasitic tablet for dogs using cryodestruction of plant materials, which showed 100% efficacy against Otodectes cynotis ticks by the second day and 93.76% efficacy against Ixodes, Dermacentor, and Rhipicephalus ticks.
39 citations
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January 2019 in “Journal of Dermatological Treatment” This review found topical ketoconazole to be highly effective against Malassezia-related skin conditions, though other treatments may outperform it for Tinea and Candida infections.
29 citations
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August 2020 in “Parasitology” This review found that tea tree oil, especially terpinen-4-ol, may be the most effective treatment for Demodex-related diseases, but more research is needed to improve treatment efficacy and reduce side effects.
April 2026 in “International Journal of Agriculture and Food Science” In this case report, a young goat with mixed ectoparasitic infestations including Psoroptes spp. showed significant clinical improvement and resolution of skin lesions after treatment with ivermectin-based therapy and supportive care, illustrating the importance of early diagnosis and comprehensive management for recovery.
November 2023 in “Veterinary Science and Medicine Journal” This case study describes a mixed breed dog with complex dermatitis caused by infections of Demodex sp, Sarcoptes scabiei, and Malassezia sp and reports that a combination of ivermectin treatment and sulfur shampoo improved the dog's symptoms after 14 days.
165 citations
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February 2014 in “Phytotherapy Research” Myrtle has various health benefits and potential for medicine development.
70 citations
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July 2020 in “Pharmacological Reports” This review discusses the antiviral potential of cepharanthine against SARS-CoV-2, noting its effectiveness in preclinical models but presenting no new clinical results.
1 citations
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January 2014 in “The journal of advances in parasitology” This case study in a German Shepherd with mixed ectoparasite and bacterial infections demonstrates that a combined therapeutic approach significantly improved the animal's skin condition and led to recovery.
October 2025 in “Buletin Veteriner Udayana” This case report described a young Himalayan kitten in Indonesia with notoedric mange, treated successfully with topical selamectin and sarolaner, highlighting the importance of early diagnosis and management to prevent reinfestation, especially in urban areas.
April 2023 in “Jurnal Sain Veteriner” This case report describes a Persian cat with Acute Moist Dermatitis triggered by ectoparasite infestation and complicated by systemic infection, which required intensive treatment including antiparasitics and antibiotics.
May 2020 in “International journal of current microbiology and applied sciences” This case report describes a 3-year-old pug with mixed Demodicosis and Staphylococcal infections that recovered completely after two months of combined antiparasitic, antibacterial, anti-inflammatory treatment, and supportive therapy.
36 citations
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March 2004 in “AIDS” This case report highlights that immune reconstitution after starting HAART can lead to demodex folliculitis in HIV patients, emphasizing the need to consider it in differential diagnosis of skin eruptions.
18 citations
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July 2001 in “Australian veterinary journal” This case study describes a cat with concurrent cutaneous xanthomas, demodicosis, and dermatophytosis, which suggests potential primary hyperlipidaemia as the underlying cause for its symptoms.
This review examines cepharanthine's antiviral potential against COVID-19 and finds no clinical results yet; it highlights cepharanthine as a potent inhibitor of coronavirus in preclinical models.
March 2026 in “Buletin Veteriner Udayana” This case report describes a 4-month-old domestic dog suffering from emaciation alongside Malasseziosis and Ehrlichiosis, showing significant clinical improvement after treatment, including dietary changes, medicated bathing, antiparasitic, antibiotic therapy, and supportive care.
In this study, researchers explored the diverse causes of alopecia in dogs, highlighting how factors such as infection, hormonal imbalances, and genetic conditions contribute to hair loss, and emphasized the importance of tailored diagnostics and treatment strategies.
July 2025 in “Buletin Veteriner Udayana” This study reports a case of generalized dermatitis in a mixed-breed German Spitz due to Sarcoptes scabiei and Malassezia sp. infection, treated with ivermectin and fluconazole, plus supportive therapies, resulting in marked lesion reduction though not full recovery.
January 2024 in “Veterinary Science and Medicine Journal” In this case report, a 1.5-year-old Pomeranian named Beb with respiratory and skin issues was diagnosed with pneumonia and demodecosis; following a two-week treatment including antibiotics, ivermectin, and supportive care, Beb's symptoms resolved, and hair regrowth was observed.
October 2023 in “Veterinary Science and Medicine Journal” In this case report, a 2-year-old cat with bilateral otitis externa and scabiosis was treated with a combination of antiparasitic, antibiotic, antifungal, and anti-inflammatory medications, leading to significant clinical improvement after 10 days.
September 2023 in “Journal of Parasite Science” In this case report, a 12-year-old female pug mix dog diagnosed with demodicosis and a Malassezia infection showed improvement in symptoms after a week of treatment with antiparasitic drugs, antibiotics, antifungal medications, antihistamines, and vitamins, evidenced by reduced scratching intensity.
April 2019 in “Journal of parasitic diseases” This case report describes a male Persian cat with Cheyletiella spp. infestation causing alopecia and pruritus, which was successfully treated using ivermectin and selenium sulphide shampoo.
January 2018 in “INTAS POLIVET” In this clinical case report, a Labrador dog with multiple skin issues was successfully treated for Demodex mites and Pemphigus foliaceus using Prednisolone, Cephalexin, Amitraz, Ivermectin, and Ketoconazole, resulting in an uneventful recovery.
June 2014 in “Basic & Clinical Pharmacology & Toxicology” This study found that alkaloids isolated from Cucumis metuliferus fruit pulp demonstrated antiviral activity against IBDV in chicken embryo fibroblast cells and NDV in 10-day-old embryonated chicken eggs, while being non-cytotoxic.
August 2004 in “Veterinary Dermatology” This case series described opportunistic skin conditions in three diabetic cats with additional immunosuppressive diseases, highlighting various treatments and outcomes, including a notable demodicosis recovery.
March 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that type 2 immunity, especially involving ILC2 cells, helps maintain skin homeostasis by regulating the proliferation and community stability of hair follicle epithelial cells in the presence of Demodex mites.
3 citations
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May 2024 in “Journal of Drug Delivery and Therapeutics” This review examines the therapeutic potential of Aftimoon (Cuscuta reflexa), focusing on its pharmacological properties and traditional uses in Unani medicine for various ailments, and highlighting its range of biological activities, including antioxidant and anti-inflammatory effects.
4 citations
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December 2017 in “International journal of research in ayurveda and pharmacy” This review discusses the traditional and pharmacological uses of Cuscuta reflexa, but it reports no new clinical results, calling attention to its potential antihypertensive, antidiabetic, and antioxidant properties.
125 citations
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May 2019 in “Phytomedicine” This review discusses the historical development, mechanisms of action, and potential new clinical applications of the drug cepharanthine, highlighting its multi-faceted pharmacological properties; it reports no new clinical results.
1 citations
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December 2011 in “Arzneimittelforschung” This study found that the compound 9,11-dehydrocortexolone 17alpha-butyrate (CB-03-04) showed strong local antiandrogenic activity in animal models, suggesting potential for treating prostate conditions.