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Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.

Caffeine may help reduce stress-induced hair loss.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.

Certain gene variations might be linked to severe acne in women but not in men.

The tobacco leaf extract may help hair grow and could treat hair loss.

Iodine-deficient diets and antithyroid substances affected rat growth and behavior, but most adapted with positive weight gain.

One cat with low thyroid hormone had growth issues, and another with high thyroid hormone had skin problems; both got better with treatment.

Orthognathic surgeons play a key role in modifying masculine facial features to be more feminine, often improving transgender women's quality of life.

DHEA improved brain function and behavior in old monkeys and had additional health benefits.

Different botulinum toxin products and concentrations can effectively reduce sweating, itching, bladder pressure, hair loss, and muscle spasms.

Convolvulus arvensis ethanolic extract can potentially promote hair growth and reduce hair loss.

The document concludes that non-binary individuals need compassionate support and recognition in healthcare, without being pathologized.

The modified Ferriman-Gallwey method is a useful tool for diagnosing hirsutism.

Facial feminization surgery is effective in helping transgender women appear more feminine and has high patient satisfaction.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Probiotic bacteria improved skin and hair health in aged mice.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

Best hair growth results from combining finasteride and minoxidil.

Jasmonic acid and its derivatives play important roles in plant health and have potential uses in medicine and agriculture.

Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

Human hair follicles can make and process prostaglandins, which may affect hair growth.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Tofacitinib was effective in treating hair loss in two patients with alopecia universalis.

*Acorus calamus* has many medicinal benefits but needs more safety research.

Bee venom might be a good alternative treatment for various skin conditions because it has many healing properties.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Finasteride blocks progesterone's effect on absence seizures in rats.