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Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Apremilast was not effective in treating moderate-to-severe alopecia areata.

Minoxidil boosts hair growth by triggering growth factor release from specific stem cells.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Nanotechnology improves hair care products by enhancing ingredient stability, targeting treatment, and reducing side effects, but more research on its toxicity is needed.

Ginsenoside F2 from ginseng may increase hair growth better than standard treatments by affecting cell growth signals.

Most Hairless gene mutations reduce its ability to work with the Vitamin D Receptor, which might explain a certain type of hair loss.

Basal cell carcinomas have much higher levels of Vitamin D3 receptors compared to healthy skin.

Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.

Melatonin may help treat PCOS symptoms in rats.

Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.

New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.

Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.

Some plants used in traditional medicine may help treat cancer because they contain proteins that can inactivate ribosomes.

Iron deficiency may contribute to hair loss.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Fetal cells could improve skin repair with minimal scarring and are a potential ready-to-use solution for tissue engineering.

Finasteride treats enlarged prostate, improves urinary flow, but may cause sexual side effects.

S100A3 protein is crucial for hair shaft formation in mice.

Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Finasteride may help reduce symptoms in male Tourette syndrome patients.

Nanoemulsion-based drug delivery systems are versatile and have potential for treating various medical conditions and improving vaccines.

Ephrins slow down skin and hair follicle cell growth.

Micropigmentation is a widely accepted tattooing technique for hiding cosmetic issues and medical uses, with permanent results and few side effects, but risks infection if not done with sterile tools.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Blocking CRF-R1 can reduce alcohol intake in stressed mice.