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PPAR agonists show promise for skin conditions but need more research before being a main treatment.

The document concludes that there are various treatments for different types of alopecia, but more research is needed for evidence-based treatments.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Stress and emotional factors can worsen skin conditions by affecting the immune system.

Certain liver diseases respond well to specific treatments and have varying risks for liver cancer.

Apremilast may help treat lichen planopilaris and frontal fibrosing alopecia when other treatments fail.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Dengue virus can infect human hair follicle cells and may cause hair loss.

Different immune responses cause hair loss in scalp diseases, with unique patterns in scalp psoriasis possibly protecting against hair loss.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Recognizing and treating skin symptoms in essential thrombocythemia is crucial for patient quality of life.

Early treatment with immunoglobulin and aspirin reduces heart complications in children with Kawasaki disease.

Licorice has many traditional health benefits, but more research is needed to fully support these claims.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.

Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.

Early regulatory T cells are crucial for normal skin pigmentation.

UV light helped human hair transplants survive in mice without broad immunosuppression.

Lung and liver macrophages protect our tissues and their dysfunction can cause various diseases.

Cordyceps militaris is a promising, cost-effective medicinal fungus with health benefits and efficient production methods.

Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.

The cause of Frontal fibrosing alopecia, a type of hair loss, is complex, likely involving immune responses and genetics, but is not fully understood.

Licorice has many health benefits but should be used carefully due to possible side effects.

Myotonic Dystrophy may age cells faster, and drugs that target aging could be potential treatments.

PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.

The document suggests a rare skin condition might be caused by a genetic phenomenon.

The document concludes that various skin conditions have specific treatments, ranging from antihistamines for urticaria to surgery and medication for tumors and chronic skin diseases.