August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This source provides supplementary materials for the Carnivore Follicular Integrity Framework, a theoretical model proposing that animal-based diets may support hair follicle stability through several biological mechanisms. The materials include definitions, nutrient tables, and mechanistic notes but do not report empirical results.
August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This record provides supplementary materials for a theoretical model suggesting that animal-based diets may support hair follicle stability through various biological mechanisms, including regenerative peptides and anti-glycation protection.
This theoretical research project proposes the Carnivore Follicular Integrity Framework, suggesting that animal-based diets may support hair follicle stability through various evolutionary and mechanistic pathways.
9 citations
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March 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” This symposium reviewed various advances in understanding and potentially reversing skin aging, with no new experimental results reported.
In this research presented at the BEYOND Biohacking Conference 2026, a regenerative skincare serum using plant-derived Consortia Factors® showed significant age spot lightening and improvements in skin smoothness, firmness, and radiance over eight weeks in a study with 35 women.
This research reports that transglucosylation significantly improved the water solubility of baicalin through the synthesis of baicalin glucosides, with BG1 and BG2 showing enhanced solubility and potential biological activity similar to baicalin in antioxidant and anti-glycation assays.
January 2017 in “Clinical approaches and procedures in cosmetic dermatology” This review explores the role of advanced glycation end products in skin aging and their interaction with oxidative stress, but reports no new clinical findings.
280 citations
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July 2018 in “Antioxidants” This review discusses the role of reactive oxygen species in wound healing, highlighting potential strategies like mitochondrial-targeted antioxidants for managing non-healing chronic wounds, and reports no new clinical results.
7 citations
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March 2023 in “Antioxidants” This study confirmed the antioxidant role of rosemary, suggesting its potential use in treating inflammatory and infectious skin conditions, but emphasizes that more large-scale controlled trials are necessary to fully understand its clinical impact.
1 citations
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April 2015 in “InTech eBooks” RAGE is a potential target for melanoma treatment, but its effectiveness is uncertain due to variable expression levels.
November 2022 in “Journal of Investigative Dermatology” This study developed a chalcone-based molecule that significantly increased tyrosinase inhibition and solubility, showing potential as a safe and effective skin depigmenting and antiaging agent, with supportive epigenetic and antioxidant properties observed in vitro.
This study identified pectin in early immature durian fruits and found that pectin-oligosaccharides derived from them show stronger antioxidant and antiglycation activities, with potential applications in cosmetic products.
January 2026 in “Molecules” This study found that DHA, a derivative of artemisinin, shows potential as a cosmetic ingredient due to its anti-aging, anti-hair loss, antibacterial, whitening, and anti-glycation activities.
1 citations
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January 2022 in “Journal of experimental and clinical medicine” This review examines the relationship between glycation, insulin resistance, and PCOS, discussing various treatments and highlighting M. oleifera and S. platensis as potential therapeutic agents, but reports no new clinical results.
November 2025 in “Clinical Cosmetic and Investigational Dermatology” This study found that a combination of five medicinal plants traditionally used in Chinese medicine significantly improved skin repair and delayed aging markers in laboratory models, suggesting synergistic anti-aging effects over individual ingredients.
70 citations
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April 2013 in “Endocrine” This review found that lifestyle changes, such as diet and exercise, are beneficial for managing metabolic and endocrine abnormalities in obese patients with PCOS and suggests combining these with anti-obesity agents for enhanced effects.
4 citations
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August 2025 in “Scientific Reports” This study found that hair analysis is an effective non-invasive method for assessing metabolic fluctuations, showing stable advanced glycation end products levels that correlate with age and differ significantly between diabetic and non-diabetic rats.
May 2026 in “Commagene Journal of Biology” This review found that anti-aging peptides show promise in cosmeceuticals due to their targeted actions to rejuvenate skin, but challenges like peptide stability, penetration, and limited clinical data limit their current effectiveness.
March 2026 in “Aging Research” This review provides a comprehensive synthesis of skin aging research, highlighting the interplay of genetic and environmental factors, cellular mechanisms, and advances in diagnostic and therapeutic strategies, while also addressing current debates and future directions in the anti-aging field.
August 2023 in “İzmir tepecik eğitim hastanesi dergisi” This study suggests that the role of vitamin 25(OH)D in the pathogenesis of PCOS and diminished ovarian reserve may be independent of serum vitamin 25(OH)D levels.
10 citations
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November 2015 in “Experimental Dermatology” The study observed that mRAGE expression is prevalent in keratinocytes of the healthy human epidermis and may regulate inflammation and apoptosis to maintain skin homeostasis rather than responding to aging processes.
1 citations
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February 2025 in “South Asian Research Journal of Pharmaceutical Sciences” This study used in-silico molecular docking to evaluate the antidiabetic potential of Eclipta alba leaf flavonoids, finding that compounds like apigenin, syringic acid, and vanillic acid effectively bind to the target protein aldose reductase, suggesting a promising inhibitory action.
April 2025 in “Cosmetics” In this study, synthesized composite nanocarriers containing ribose and peptides demonstrated enhanced transdermal delivery, improved uptake by skin cells, promoted cell proliferation, enhanced antioxidant enzyme activities, and increased autophagy, suggesting a potential for more effective skin anti-aging treatments.
17 citations
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February 2023 in “Cosmetics” This study explores the use of bioinspired 3D printed hollow microneedles, which may offer improved delivery of anti-wrinkle formulations, and reviews the current landscape and challenges of existing wrinkle treatments and microneedle technology.
5 citations
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June 2025 in “Advances in Therapy” This narrative review reports that metformin, traditionally used for type 2 diabetes management, may offer therapeutic benefits for various skin disorders, such as acne, rosacea, and psoriasis, due to its anti-inflammatory and other beneficial properties, warranting further exploration in dermatology.
16 citations
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March 2023 in “Clinical Cosmetic and Investigational Dermatology” This study demonstrated that regular use of LactoSporin cream for 10 weeks significantly reduced wrinkles and fine lines in healthy female participants, although improvements in skin elasticity and hydration were not significantly better than placebo when measured by certain instruments.
September 2025 in “International Journal of Molecular Sciences” This review examined the potential effects of Kampo medicine Hangeshashinto on oral mucositis, highlighting that several natural products in its composition may inhibit intracellular AGEs, reduce inflammation from extracellular AGEs, and suppress cytotoxicity in stomatitis.
January 2019 in “Springer eBooks” Modified HDL can better deliver drugs and genes, potentially improving treatments and reducing side effects.
883 citations
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August 2016 in “Nature Reviews Disease Primers” This review discusses the current understanding of polycystic ovary syndrome, focusing on its epidemiology, pathophysiology, diagnosis, management, and future research directions, but reports no new clinical results.
467 citations
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October 2014 in “European Journal of Endocrinology” This paper reviews the diagnostic criteria, etiological factors, and treatment approaches for PCOS, highlighting the importance of considering metabolic issues such as insulin resistance and obesity, but reports no new findings.