research Hydrogen Peroxide Disrupts Scarless Fetal Wound Repair
Hydrogen peroxide can cause scars by changing healing processes and increasing certain protein levels.
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research CD4+CD25+FoxP3+ Regulatory Tregs Inhibit Fibrocyte Recruitment and Fibrosis via Suppression of FGF-9 Production in the TGF-β1 Exposed Murine Lung
Special immune cells called Tregs can help prevent lung scarring by blocking a specific growth factor.
research Cellular Senescence in Tissue Repair: Every Cloud Has a Silver Lining
Cell aging can be both good and bad for tissue repair.
research Dermal Fibrosis in Male Pattern Hair Loss: A Suggestive Implication of Mast Cells
Mast cells might contribute to hair loss by causing skin thickening.
research ADM Scaffolds Generate a Pro-Regenerative Microenvironment During Full-Thickness Cutaneous Wound Healing Through M2 Macrophage Polarization via Lamtor1
ADM scaffolds help skin heal by promoting a healing-type immune response.
research Therapeutic Potential of Endogenous Stem Cells and Cellular Factors for Scar-Free Skin Regeneration
Using skin stem cells and certain molecules might lead to scar-free skin healing.
research Connective Tissue Sheath of Hair Follicle Is a Major Source of Dermal Type I Procollagen in Human Scalp
The hair follicle's connective tissue is a key source of a certain collagen in human scalp skin.
research Clinical Management of Acral Lick Dermatitis in Dogs: Fluoxetine vs Clomipramine
Both fluoxetine and clomipramine effectively treat dog lick dermatitis, but fluoxetine works faster with lower recurrence, while clomipramine has fewer side effects.
research Implanted Hair-Follicle-Associated Pluripotent Stem Cells Aid Wound Healing and Reduce Scarring in Mice
Implanted special stem cells from hair follicles helped heal wounds faster and with less scarring in mice.
research Acne Keloidalis Nuchae Successfully Treated with Halobetasol 0.01% and Tazarotene 0.045% Lotion
A new lotion with halobetasol and tazarotene successfully treats acne keloidalis nuchae.
research BH03: Systemic Sclerosis and Frontal Fibrosing Alopecia: A Novel Combination of Scarring Alopecia
A woman with systemic sclerosis developed a unique scarring hair loss combining features of systemic sclerosis and frontal fibrosing alopecia.
research Editors' Picks
Collagen VII helps skin heal and stay strong, sirolimus may lower skin cancer risk in kidney transplant patients, high-molecular-mass hyaluronan helps naked mole rats resist cancer, dermal γδ T cells aid in hair growth in rodents, and overexpression of IL-33 in mouse skin causes itchiness, offering a model for studying allergic inflammation treatments.
research SFRP2/DPP4 and FMO1/LSP1 Define Major Fibroblast Populations in Human Skin
Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.
research Androgenetic Alopecia and Microinflammation
Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.
research dsRNA Released by Tissue Damage Activates TLR3 to Drive Skin Regeneration
Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.
research Dermal White Adipose Tissue: A New Component of the Thermogenic Response
Skin fat helps with body temperature control and has other active roles in health.
research A Nude Mouse Model of Hypertrophic Scar Shows Morphologic and Histologic Characteristics of Human Hypertrophic Scar
Nude mice with grafted human skin developed scars similar to human hypertrophic scars.
research Perifollicular Fibrosis: Pathogenetic Role in Androgenetic Alopecia
Androgen hormones cause hair follicle scarring in hair loss, and finasteride helps reduce it.
research Anabolic-Androgenic Steroids and Cardiovascular Risk
Using steroids can increase the risk of heart problems.
research Minoxidil Stimulates Elastin Expression in Aortic Smooth Muscle Cells
research Friends Turned Foes: Angiogenic Growth Factors Beyond Angiogenesis
Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
research Complications in Hair-Restoration Surgery
Hair restoration surgery can have complications; success depends on patient education, careful planning, and proper execution.
research Acquired Trichomegaly of the Eyelashes and Hypertrichosis Induced by Bimatoprost
Bimatoprost can cause longer, thicker, darker eyelashes and eyebrows.
research Stimulation of Elastin Expression by Minoxidil in Chick Skin Fibroblasts
Minoxidil boosts elastin production, potentially helping skin diseases.
research Thermal Imaging and Dermoscopy for Detecting Inflammation in Frontal Fibrosing Alopecia
Infrared thermography, especially with dermoscopy, improves accuracy in diagnosing active hair loss due to inflammation.
research Demethylation of ITGAV Accelerates Osteogenic Differentiation in a Blast-Induced Heterotopic Ossification In Vitro Cell Culture Model
Removing a methyl group from the ITGAV gene speeds up bone formation in a specific type of bone disease model.
research Wound-Induced Hair Neogenesis: A Novel Paradigm for Studying Regeneration and Aging
Wounds can regenerate hair in young mice, but this ability declines with age, offering insights for improving tissue regeneration in the elderly.
research Are Fingernails a Key to Unlocking the Puzzle of Mammalian Limb Regeneration?
Nail stem cells and Wnt signaling are important for fingertip regeneration but not sufficient for regenerating more complex limb structures.
research Non-Infective Mucocutaneous Presentations of Human Immunodeficiency Virus Infection
Most HIV patients develop skin symptoms that can indicate the stage of their disease.
research CD8-Positive Lymphocytes in Graft-Versus-Host Disease of Humanized NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ Mice
CD8+ T cells play a key role in graft-versus-host disease in certain mice models.