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Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

Some postmenopausal women with frontal fibrosing alopecia stopped losing hair with finasteride treatment, hinting at a possible hormonal cause.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Lichen planus is a skin condition that can resolve on its own, is linked to hepatitis C, and increases the risk of skin cancer.

Superficial granulomatous pyoderma is a unique, mild form of skin disease that often heals without strong medication and responds well to milder treatments.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Women with PCOS and higher androgen levels are more likely to have fatty liver disease.

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

Folliculitis decalvans is a rare scalp condition causing scarring hair loss, treated with long-term antibiotics and other medications, but it often comes back and is hard to manage.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

The treatment helped reduce symptoms and stabilize the hairline in most patients with Frontal Fibrosing Alopecia, but hair regrowth was limited.

Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.

Skin fat helps with body temperature control and has other active roles in health.

Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

NF-κB is crucial for zebrafish heart repair, affecting heart cell growth and repair processes.

Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.

Platelet-rich plasma may help in skin and hair treatments, and with muscle and joint healing, but more research is needed to fully understand its benefits and limitations.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.

Skin problems can be caused or worsened by physical forces and pressure on the skin.

The document concludes that early recognition and treatment of primary cicatricial alopecia is crucial to prevent permanent hair loss.

RTA 408 cream protects mice from radiation skin damage.