research Noncoding dsRNA Induces Retinoic Acid Synthesis to Stimulate Hair Follicle Regeneration via TLR3
Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.
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research The Phytocannabinoid (–)-Cannabidiol Operates as a Complex, Differential Modulator of Human Hair Growth: Anti-Inflammatory Submicromolar Versus Hair Growth Inhibitory Micromolar Effects
CBD can either reduce inflammation and not affect hair growth at low levels or inhibit hair growth at high levels.
research dsRNA Released by Tissue Damage Activates TLR3 to Drive Skin Regeneration
Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.
research Anti-Aging Potential of Gypenosides Fraction Obtained from Naturally Grown Gynostemma Pentaphyllum in Ulleungdo Island and Its Seven New Gypenosides
Gypenosides from Gynostemma pentaphyllum were found to have anti-aging effects, increasing skin collagen and reducing wrinkles.
research Oncostatin M Is Upstream of JAK-STAT Signaling During the Murine Hair Cycle
Blocking Oncostatin M's role in the JAK-STAT pathway can stimulate hair growth in mice.
research Diverse Cellular Players Orchestrate Regeneration After Wounding
Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.
research Effect of Prostaglandin D2 on Hair Follicle Growth and Its Impact on Hair Follicle Stem/Progenitor Cells
Blocking Prostaglandin D₂ may help treat hair loss.
research Effect of Lithocholic Acid as a Ligand of Vitamin D Receptor on Hair Growth in Alopecia
Lithocholic acid helps hair growth and regeneration in alopecia by activating vitamin D receptors.
research Signaling Networks Between Stem Cell Precursors, Transit Amplifying Progenitors, and Their Niche in Developing Hair Follicles
Blocking Prostaglandin D₂ (PGD₂) could help treat hair loss.
research An Immune Regulatory CCT Repeat Containing Oligodeoxynucleotide Capable of Causing Hair Loss in Male Mice
A specific DNA sequence caused hair loss in male mice by activating immune cells and increasing a certain immune signal.
research Wound Healing: A Cellular Perspective
The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
research Single-Cell Analysis Reveals Fibroblast Heterogeneity and Myeloid-Derived Adipocyte Progenitors in Murine Skin Wounds
The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.
research Hair Follicles’ Transit-Amplifying Cells Govern Concurrent Dermal Adipocyte Production Through Sonic Hedgehog
Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.
research To Control Site-Specific Skin Gene Expression, Autocrine Mimics Paracrine Canonical Wnt Signaling and Is Activated Ectopically in Skin Disease
The research suggests that a specific skin gene can be controlled by signals within and between cells and is wrongly activated in certain skin diseases.
research Wound-Induced Hair Neogenesis: A Novel Paradigm for Studying Regeneration and Aging
Wounds can regenerate hair in young mice, but this ability declines with age, offering insights for improving tissue regeneration in the elderly.
research Toll-Like Receptor 3 Agonist, Polyinosinic-Polycytidylic Acid, Upregulates Carbonic Anhydrase II in Human Keratinocytes
A substance called poly(I:C) increases a protein called carbonic anhydrase II in skin cells, which might help with skin defense and healing.
research IL-36α Promoted Wound-Induced Hair Follicle Neogenesis via Hair Follicle Stem/Progenitor Cell Proliferation
IL-36α helps grow new hair follicles and speeds up wound healing.
research Transient Calcium Entry by Plasmalogen-Mediated Activation of Receptor Potential Cation Channel Promotes AMPK Activity
Plasmalogens activate a channel in cells that may stimulate hair growth.
research Automated Machine Learning Analysis of Patients With Chronic Skin Disease Using a Medical Smartphone App: Retrospective Study
Machine learning can predict symptoms and quality of life in chronic skin disease patients using smartphone app data, and shows that app use varies with patient characteristics.
research Topical SCD-153, A 4-Methyl Itaconate Prodrug, For The Treatment Of Alopecia Areata
SCD-153 shows promise as an effective topical treatment for alopecia areata.
research TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling
TLR2 is important for hair growth and can be targeted to treat hair loss.
research TLR3 Signaling Modulates Immunomodulatory Property of Human Periodontal Ligament Stem Cells
TLR3 signaling enhances the immunosuppressive properties of human periodontal ligament stem cells.
research Tracing Immune Cells Around Biomaterials With Spatial Anchors During Large-Scale Wound Regeneration
Immune cells are essential for skin regeneration using biomaterial scaffolds.
research Activation of TLR3 Enhances Stemness and Immunomodulatory Properties of Periodontal Ligament Stem Cells
Activating TLR3 improves the healing and immune properties of periodontal ligament stem cells.
research Vitamin A in Skin and Hair: An Update
Vitamin A is important for healthy skin and hair, influencing hair growth and skin healing, but UV light reduces its levels.
research Interleukin-6 from Adipose-Derived Stem Cells Promotes Tissue Repair by Increasing Cell Proliferation and Hair Follicles in Ischemia/Reperfusion-Treated Skin Flaps
IL-6 from stem cells helps repair skin and grow hair.
research A Population of Radio-Resistant Macrophages in the Deep Myenteric Plexus Contributes to Postoperative Ileus Via Toll-Like Receptor 3 Signaling
Certain immune cells worsen post-surgery gut paralysis by activating a specific immune response.
research Stat3 Partly Inhibits Cell Proliferation Via Direct Negative Regulation of FST Gene Expression
The protein STAT3 slows down cell growth by blocking the FST gene, which affects hair development in sheep.
research The Efficacy of Adipose-Derived Stem Cells in Burn Injuries: A Systematic Review
Adipose-derived stem cells help heal burns but need more research.
research Enzymes
Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.