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Premature graying of hair may suggest health issues and currently lacks effective treatments.

Substance P may worsen acne by increasing inflammation, but corticosteroids might help by reducing this effect.

Phosphatidic acid may help hair grow by affecting cell growth pathways.

Mitoxantrone is effective for treating acute leukemia, especially in older patients, with a lower risk of heart damage.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.

Vitamin C helps adipose-derived stem cells grow and may support hair growth.

Children generally have milder SARS symptoms than adults, with good outcomes and no deaths reported, but long-term effects are unclear.

Distinct β-catenin patterns are linked to cell growth, not cell death, in lung cancer.

Basal cell carcinomas have much higher levels of Vitamin D3 receptors compared to healthy skin.

MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.

S100A3 protein is crucial for hair shaft formation in mice.

Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

The document concludes that treatment for cutaneous T-cell lymphoma should be customized to each patient's disease stage, balancing benefits and side effects, with no cure but many patients living long lives.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Researchers isolated a new type of stem cell from mouse skin that can renew itself and turn into multiple cell types.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

Cells from a skin condition can create new hair follicles and similar growths in mice, and a specific treatment can reduce these effects.

Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Madarosis is the loss of eyelashes and eyebrows due to various health issues and requires thorough examination to diagnose and treat the underlying cause.

Dihydrotestosterone increases certain inflammatory signals in skin cells, potentially contributing to acne.

Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.

The document concludes that managing non-classical congenital adrenal hyperplasia in females requires personalized treatment, genetic counseling, and a team of specialists.

The Ovol2-Zeb1 circuit is crucial for skin healing and hair growth by guiding cell movement and growth.

A team approach is crucial for managing PCOS, with dermatologists playing a key role.

Progesterone and related compounds may help control seizures linked to the menstrual cycle but have limitations that need addressing.

Finasteride can cause one-sided breast enlargement, which disappears after stopping the drug.

Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.