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The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.

New treatments for lupus show promise, but more research is needed, especially for children.

Biologic therapies can cause various adverse events, but allergy/immunology clinicians can manage them.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Different causes of beard hair loss have various treatments, including medications, lifestyle changes, and procedures to stimulate hair growth.

Using low-dose IL-2 to increase regulatory T cells might be a safe way to treat type 1 diabetes without severe side effects.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

Severe digestive issues in DRESS need early endoscopy for better treatment.

Transplanted hair follicles can change and adapt to new areas of the body, with the immune system possibly playing a role in this adjustment.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

Targeted cancer therapies have a significant but lower risk of causing hair loss compared to chemotherapy.

The monkey's hair loss was due to an autoimmune disease, not genetics.

A woman with scalp lymphoma and hair loss improved with radiotherapy, highlighting the need for biopsies in similar cases.

Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.

A 16-year-old boy with Castleman's disease and lupus was successfully treated and showed no recurrence.

Hidradenitis suppurativa is a chronic skin condition more common in women, linked to genetics and lifestyle factors, and associated with various other health issues.

Systemic lupus erythematosus is diagnosed earlier in males than females.

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

Liver transplantation is a viable option for children with propionic acidemia, improving quality of life and diet, but does not remove all risks and long-term brain outcomes are uncertain.

A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

iNKT cells can help prevent and treat alopecia areata by promoting hair regrowth.

Some diseases can improve the outcomes of other diseases, leading to new treatment possibilities.

A woman with a rare scalp lymphoma had unusual hair loss after treatment.

Best treatment for Frontal Fibrosing Alopecia is 5-alpha-reductase inhibitors and intralesional corticosteroids.

Lupus is a complex disease that requires personalized treatment because it varies greatly between individuals.

The document concludes that non-scarring alopecias can be reversed, but scarring alopecias cause permanent hair loss.