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High doses of cyproterone acetate are linked to an increased risk of developing meningioma.

Putting ketoconazole on the skin can help mice grow hair.

5α-Reductase inhibitors can negatively affect male sexual function and, in some cases, significantly reduce sperm count, but these effects may be reversible.

Spironolactone might cause painful intercourse and decreased sexual arousal in women.

Isoflavone may help manage PCOS symptoms, but its effectiveness is uncertain.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

Finasteride negatively affects fish reproduction and gonadal development.

Taking Saw palmetto and Pygeum africana can change the levels of certain steroids in urine, which could cause confusion in doping tests.

A herbal mix with chickpea, holy basil, and nut grass extracts grew rat hair well, similar to a common hair growth drug.

Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.

Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.

Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.

Some herbs show promise as antiandrogenic agents.

Cyproterone acetate reduced hair growth in most hirsute females and made hair softer, thinner, and lighter.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Fluridil safely promotes hair growth in men with androgenetic alopecia.

Liquorice may reduce testosterone and affect male reproductive organs, potentially helping treat conditions like prostate cancer.

Finasteride caused enlarged breast tissue in a 62-year-old man.

Germacrone in Curcuma aeruginosa extract degrades at high temperatures but is stable in certain solutions and unaffected by pH levels.

Spironolactone is effective for acne, hidradenitis suppurativa, female hair loss, and hirsutism but is underused in dermatology.

New steroids were effective in blocking male hormone receptors in hamster prostates.

Two types of 5α-reductase are in dog skin, which might make dutasteride better than finasteride for treating dog hair loss.

Environmental factors and exposure to toxins may contribute to male infertility by affecting sperm and hormone function.

Spironolactone may cause sexual pain and arousal issues in women, which can improve after stopping the drug and using hormone cream.

Fluridil safely promotes hair growth in men with androgenetic alopecia.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Ginseng, especially red ginseng, may help regrow hair and block a hair loss-related enzyme.