11 citations
,
January 1991 in “Urology” This article reviews the potential of combining antiandrogenic and antiestrogenic treatments for BPH, highlighting aromatase inhibitors, but presents no new clinical results; further research is needed.
1 citations
,
May 2009 in “Annales de Dermatologie et de Vénéréologie” This article reviews environmental factors contributing to androgenic alopecia and emphasizes the importance of giving patients advice to manage hair loss; it reports no new clinical findings.
November 2025 in “Fertility Gynecology and Andrology” This study highlights that polycystic ovary syndrome develops through genetic and environmental factors, with insulin resistance as a key mechanism, impacting the risk of metabolic and cardiovascular conditions.
73 citations
,
February 2007 in “The American Journal of Medicine” This review discusses the diagnosis, symptoms, metabolic complications, and treatment of polycystic ovary syndrome, offering no new clinical findings but includes a summary of treatment recommendations.
24 citations
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January 2011 in “Sexual Development” This study observed that chemically-induced intersex frogs displayed altered brain mRNA profiles, with finasteride increasing certain hormone-related gene expressions and fadrozole reducing aromatase activity without affecting gene transcript levels.
January 2025 in “International Journal of Unani and Integrative Medicine” This review explores hirsutism in women with PCOS, analyzing its pathophysiology and management through both modern medicine and Unani perspectives, and suggests combining these approaches for more holistic care, while calling for future research to enhance treatment efficacy and safety.
December 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Flutamide, an oral anti-androgen therapy, is effective in treating female pattern hair loss, even without systemic androgen excess.
70 citations
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February 2025 in “Journal of Ovarian Research” This review provides an analysis of the physiological and pathological aspects of polycystic ovary syndrome, emphasizing endocrine, metabolic, and inflammatory dimensions, but reports no new clinical results.
36 citations
,
May 2017 in “The journal of sexual medicine” In this retrospective study, cyproterone acetate treatment in late-pubertal trans-girls was found to be generally safe and led to mild feminizing effects, with more rapid feminization occurring when combined with estrogens.
12 citations
,
January 1998 in “Endocrine journal” Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.
10 citations
,
December 2015 in “Clinics in Dermatology” This review highlights the eye and skin manifestations of endocrine-related metabolic diseases but provides no new clinical results.
5 citations
,
June 2010 in “Endocrinología y Nutrición” This article discusses PCOS in adolescents and highlights the importance of early diagnosis and treatment to prevent long-term health complications, noting increasing adolescent obesity may worsen symptoms.
1 citations
,
September 1981 in “PubMed” This study found that treatment with cyproterone acetate was generally successful for women with virilizing features, showing improved results in younger women and those with adrenal hirsutism, despite some side effects.
August 2023 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Minoxidil users may experience hair discoloration, especially with long-term use and a family history of gray hair.
6 citations
,
January 2017 in “Dermato-endocrinology” This study found that androsterone glucuronate (ADT-G) was the only androgenic metabolite sensitive to detecting differences between adult women with acne and controls, and its levels decreased with systemic treatment.
July 2008 in “International journal of psychophysiology” This retrospective study found that cyproterone acetate, both alone and with estrogens, was safe, well tolerated, and induced modest feminizing effects in late-pubertal transgender female adolescents.
November 2007 in “Neuro-chirurgie/Neurochirurgie” This study reported that treatment with cyproterone acetate alone and then with incremental estrogen doses induced mild feminizing effects in late-pubertal trans-girls, with further feminization observed after adding estrogen.
This review discusses the clinical forms and causes of androgenization in women, as well as therapeutic options, reporting success with antiandrogens like cyproterone acetate and spironolactone for skin symptoms, though results are not permanent.
2 citations
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July 2012 in “Obstetrics, gynaecology and reproductive medicine” This article reviews the physiology, causes, and treatments of hirsutism and reports no new research findings.
This review discusses the diagnosis, symptoms, and treatment options for polycystic ovary syndrome but reports no new research findings; the authors emphasize the importance of early diagnosis and treatment to reduce complications.
February 2020 in “Acta Scientific Women's Health” This narrative review discusses the various symptoms, diagnosis challenges, and treatment options for polycystic ovary syndrome, emphasizing the need for increased awareness and early diagnosis to prevent complications.
This article discusses the various skin side effects associated with targeted cancer therapies like tyrosine kinase inhibitors and EGF-R inhibitors but provides no new clinical findings.
This extended abstract discusses various treatments for alopecia, including low-level light therapy, which has shown promise but requires further research to establish effectiveness, especially in combination with other therapies.
October 2019 in “DOAJ (DOAJ: Directory of Open Access Journals)” This review focuses on the clinical presentation and management challenges of menopausal acne and reports no new experimental findings.
14 citations
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September 2015 in “Expert Opinion on Therapeutic Targets” This review discusses potential treatments for androgen excess in polycystic ovary syndrome and reports no new findings, emphasizing the importance of individualized antiandrogenic management to minimize side effects.
September 1997 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” The document concludes that treatments like oral anti-androgens, minoxidil, and topical spironolactone can be effective for hair loss in men and women.
September 2024 in “Journal of the American Academy of Dermatology” In this pilot study, minoxidil-treated scalp skin grafts from hair loss patients on mice showed increased expression of key anti-aging biomarkers and hair regrowth, suggesting minoxidil as a potential anti-aging agent by boosting VEGF-A production in hair follicles.
March 2026 in “Food Science & Nutrition” In this study, high-dose Arachis hypogaea root extract significantly reduced prostate weight and markers of glandular hyperplasia in testosterone-induced BPH in mice, with associated changes in inflammatory gene expression and beneficial shifts in gut microbiota.
June 2007 in “Journal of Investigative Dermatology” Title change to "Central Centrifugal Cicatricial Alopecia (CCCA)"; common in African American women; hair-grooming methods may contribute; no effective therapy found; trials needed.
32 citations
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August 1985 in “Clinical endocrinology” This study concluded that spironolactone may be an effective therapy for a subgroup of hirsute patients, as it reduced plasma testosterone and improved certain hair growth measures.