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Oral estradiol works for many transgender women but needs personalized dosing and monitoring.

The document concludes that Hidradenitis suppurativa is often underdiagnosed, lacks definitive treatment, and requires better awareness and management strategies.

Minoxidil and finasteride are the best for non-scarring hair loss; more research is needed for scarring hair loss treatments.

The document concludes that using a person's own fat cells (SVF) can significantly increase hair thickness and density, suggesting it could be a promising treatment for hair loss.

Certain skin conditions in women are linked to higher risks of metabolic syndrome and type 2 diabetes due to hormone imbalances.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Adult female acne is complex and requires a combination of treatments for effective management.

Hair loss reduces hair thickness and coverage, but drug treatments mainly revive dormant hairs rather than reverse thinning; patients often undervalue their hair loss severity.

Understanding how acne develops in different diseases could lead to new treatments.

New treatments using stem cells and other methods show promise for promoting hair growth in androgenetic alopecia.

Low-level laser therapy is safe but not significantly better than minoxidil alone for hair growth.

Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.

Hormonal changes and psychological issues can cause sexual dysfunction in postmenopausal women. Behavioral therapy is recommended first, with hormone replacement helping some symptoms but not libido. Testosterone can improve libido, but its effects on overall sexual function are unclear. Emotional and relationship issues should be addressed before using medication, and the benefits and risks of testosterone supplementation should be considered.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

DHT, a testosterone byproduct, causes male pattern baldness.

Testosterone can both promote hair growth and cause baldness by affecting hair growth signals.

Flutamide caused damage to male rat reproductive organs and may affect fertility.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

TGF-β1 increases androgen receptor activity in hair loss, but Hic-5/ARA55 can counter this effect.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Nandrolone and oxandrolone could help treat male health issues like muscle loss and low testosterone.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Finasteride effectively treats BPH but may increase sexual dysfunction risk.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Adult female acne requires a comprehensive treatment approach, including medical options and lifestyle changes, with attention to psychological well-being.

Hormone treatments can help with women's skin and hair disorders, but they need careful monitoring and more research.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.