54 citations,
January 2018 in “Scientific reports” Human hair contains diverse proteins, including keratins and histones, which could help assess hair health and aging.
54 citations,
June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Disruptions in hair follicle fibroblast dynamics can cause hair growth problems.
53 citations,
August 2019 in “American journal of human genetics” FOXN1 gene variants cause low T cells and immune issues from birth.
53 citations,
October 2014 in “Free radical biology & medicine” Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.
51 citations,
November 2011 in “Reproductive Biology and Endocrinology” About 13% of women had idiopathic hirsutism and 8.5% had polycystic ovary syndrome in a group of Iranian women.
49 citations,
July 2004 in “Anesthesiology” The document concludes that more research is needed to understand how to treat muscle pain with drugs.
48 citations,
April 2010 in “Journal of the European Academy of Dermatology and Venereology” Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.
47 citations,
February 2021 in “Pharmacological research” Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.
47 citations,
May 2020 in “Cardiovascular Research” The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.
47 citations,
September 2016 in “Reviews in endocrine and metabolic disorders” The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
47 citations,
January 2013 in “International Journal of Cosmetic Science” Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.
47 citations,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Premature graying of hair may suggest health issues and currently lacks effective treatments.
47 citations,
December 2002 in “Journal of Neurochemistry” Progesterone boosts alcohol's effect on brain, finasteride counters it.
43 citations,
July 2019 in “Stem Cells International” Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.
42 citations,
January 2021 in “Journal of Clinical Medicine” Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.
42 citations,
December 2016 in “Cell Death & Differentiation” Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.
42 citations,
May 2016 in “Annual Review of Cell and Developmental Biology” Fat cells are important for tissue repair and stem cell support in various body parts.
41 citations,
September 2012 in “Cellular and Molecular Life Sciences” MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.
41 citations,
June 2010 in “Clinics in Dermatology” Smoking harms skin health, causing slower wound healing, more wrinkles, and worsening some skin conditions, but may protect against certain others.
40 citations,
March 2018 in “Aesthetic Surgery Journal” New treatment combining PRP and SVF increases hair density in 6-12 weeks for androgenetic alopecia patients.
40 citations,
July 2015 in “Journal of Cellular Biochemistry” Cysteine helps maintain keratin production in skin cells even when iron is low.
40 citations,
May 1999 in “Journal of The European Academy of Dermatology and Venereology” Treat hair loss with finasteride, minoxidil, or surgery; consider side effects and severity.
40 citations,
May 1987 in “The Lancet” Minoxidil helps some bald men, but most lose hair again when stopping.
39 citations,
August 2016 in “Journal of Dermatological Treatment” Stem cell therapy may help treat tough hair loss cases.
39 citations,
January 2012 in “International Journal of Trichology” Melatonin solution helps treat hair loss in men and women.
38 citations,
June 2018 in “Archives of Toxicology” Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
38 citations,
December 2011 in “British Journal of Dermatology” Menopause-related hormonal changes affect hair but are not the only cause of hair changes in middle-aged women.
37 citations,
June 2021 in “Journal of the European Academy of Dermatology and Venereology” Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.
37 citations,
January 1997 in “Clinics in Dermatology” Hair problems are common and distressing for women, but increasing knowledge of treatments offers hope.
36 citations,
August 2011 in “Journal of Controlled Release” Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.