25 citations
,
October 2019 in “Journal of Endocrinological Investigation” This study reported that both drospirenone and chlormadinone acetate oral contraceptives had similar beneficial effects on clinical, metabolic, and hormonal parameters in women with polycystic ovary syndrome over six months.
22 citations
,
January 2015 in “BioMed Research International” This study reports that the burden of PCOS was higher among urban Indian adolescent females compared to their rural counterparts.
18 citations
,
January 2017 in “Dermatologic Surgery” This review examines intrinsic and extrinsic aging impacts and presents evidence-based lifestyle recommendations to complement cosmetic procedures for enhanced antiaging outcomes, but it reports no new clinical results.
17 citations
,
May 2019 in “Diabetes and Metabolic Syndrome: Clinical Research and Reviews” This study found that fasting insulin levels are associated with increased cardiovascular and metabolic risk factors in women with polycystic ovary syndrome.
17 citations
,
May 2012 in “Clinical Endocrinology” This study found that surgical normalization of testosterone in hyperandrogenic women with ovarian androgen-secreting tumors did not significantly change body weight or insulin sensitivity after 12 months.
16 citations
,
March 2018 in “Plastic and Reconstructive Surgery – Global Open” This literature review suggests that early and aggressive intervention may improve outcomes for avulsive ballistic facial injuries, although further comparative studies are needed.
16 citations
,
March 2015 in “Wiener Klinische Wochenschrift” Vitamin D deficiency is common in women with PCOS and linked to some metabolic problems, but not the main cause of their metabolic issues.
16 citations
,
May 2013 in “Urology” The authors concluded that components of metabolic syndrome were strongly associated with severe lower urinary tract symptoms in Latin American men, while alopecia was not an independent predictor.
16 citations
,
January 2012 in “Indian Journal of Endocrinology and Metabolism” This case series describes six women with both PCOS and Graves' disease, suggesting a possible shared underlying cause for their co-occurrence.
15 citations
,
January 2015 in “Dermatology Research and Practice” This study found no significant association between androgenetic alopecia and metabolic syndrome, though systolic blood pressure was higher in the alopecia group compared to controls.
15 citations
,
October 2011 in “Gynecological Endocrinology” This study found that obesity in PCOS women with biochemical hyperandrogenemia lowers androstenedione levels and increases the testosterone to androstenedione ratio, but this was not observed in women with clinical hyperandrogenemia or in controls.
14 citations
,
January 2018 in “Endocrinology and Metabolism” This study found that older age and obesity are predictors of metabolic syndrome and insulin resistance syndrome among infertile Vietnamese women with PCOS.
13 citations
,
April 2015 in “Human Reproduction” Obese Hispanic women with PCOS are at higher risk for metabolic problems than non-Hispanic white women.
12 citations
,
August 2011 in “European Journal of Endocrinology” This study found that anti-Müllerian hormone (AMH) is a valuable primary variable for classifying functional androgenization, especially in distinguishing ovarian-related groups, and supports the novel stratification system.
10 citations
,
February 2020 in “Endocrine” This study found that finasteride treatment in males with androgenetic alopecia was linked to significant changes in sperm parameters and increased testosterone levels, but no sexual dysfunction was observed, and sperm parameters returned to baseline after treatment stopped.
10 citations
,
January 2020 in “Advances in Dermatology and Allergology” This study suggests that the gene rs27647 polymorphism may play a role in the pathogenesis of severe acne vulgaris in post-adolescent male patients.
10 citations
,
August 2012 in “Clinical Pharmacokinectics” This study found that type 2 diabetes mellitus does not affect the pharmacokinetics of metformin in obese pregnant women with PCOS, suggesting no need for dosage adjustments.
9 citations
,
February 2019 in “Journal of Clinical Research in Pediatric Endocrinology” In this study, children with classical congenital adrenal hyperplasia were found to have increased epicardial fat thickness, which was associated with subclinical atherosclerosis markers and left ventricular dysfunction, especially in poorly controlled cases.
9 citations
,
January 2017 in “Ginekologia Polska” This study found that the total testosterone/dihydrotestosterone ratio correlates with a negative metabolic profile in both women with PCOS and healthy women.
8 citations
,
September 2018 in “Journal of Cosmetic Dermatology” This study found that serum irisin levels were significantly lower in patients with acne vulgaris compared to healthy controls and were negatively correlated with insulin resistance and disease severity.
8 citations
,
March 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” In this study of healthy men, low levels of testosterone and dihydrotestosterone were associated with higher body mass index, fat content, and insulin resistance, but their effects on lipid and glucose metabolism were similar in quality.
7 citations
,
January 2017 in “Journal of South Asian Federation of Obstetrics and Gynaecology” This study found that 45.8% of women with polycystic ovarian syndrome in the reproductive age group had metabolic syndrome, with low HDL and high triglycerides being significant characteristics.
6 citations
,
February 2014 in “Actas Dermo-Sifiliográficas” This study found that acanthosis nigricans and skin tags in nondiabetic, obese patients were significantly associated with higher insulin levels, suggesting they may serve as clinical markers of hyperinsulinemia.
5 citations
,
July 2016 in “Canadian Urological Association journal” This study suggests that age, androgenetic alopecia, metabolic syndrome, and free testosterone levels may significantly affect sexual function in premenopausal women.
5 citations
,
April 2014 in “Journal of Obstetrics and Gynaecology Research” This study found that young women with PCOS had normal thyroid function but showed alterations in lipid metabolism, which may predispose unmarried women in this group to cardiovascular diseases.
4 citations
,
January 2020 in “Obstetrics and Gynecology Reports” This study found that obese Egyptian women with polycystic ovary syndrome had significantly lower serum 25-OH vitamin D levels compared to non-obese women with the condition.
4 citations
,
October 2018 in “International Braz J Urol” This study found no positive association between the use of 5α-reductase inhibitors and the risk of male breast cancer.
4 citations
,
November 2016 in “Archives of Endocrinology and Metabolism” This study found that thyroid volume was increased in PCOS patients with insulin resistance, with potential influences from TSH and LH levels on these changes.
4 citations
,
January 2016 in “International journal of reproduction, contraception, obstetrics and gynecology” This study found that the FSHR Ser680Asn (rs6166) gene polymorphism is associated with an increased risk of PCOS in the examined population and could serve as a molecular biomarker for identifying risk.
4 citations
,
January 2016 in “Annals of Dermatology” This study found that men with more advanced androgenetic alopecia had increased epicardial fat thickness, suggesting a potential link to coronary risk.