63 citations
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May 2011 in “Clinical cancer research” In this study, topical CUR61414 was effective in inhibiting basal cell carcinomas in mice, but no clinical activity was observed in human trials.
14 citations
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December 2003 in “Medical Hypotheses” This paper proposes a new hypothesis that androgenic hair loss may be caused by changes in scalp vasculature due to androgen effects, but reports no new experimental results.
1 citations
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December 2013 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This review discusses the National Alopecia Areata Foundation's efforts to evaluate and advance alopecia areata research, focusing on immunology and drug development, and reports no new clinical results.
December 2023 in “Archaeopress Publishing Ltd eBooks” This source reviews historical works on cosmetics and healthcare from the Middle Ages to the Early Modern Period in Europe, highlighting the use of natural ingredients for aesthetic and medicinal purposes across various cultures, including Christian, Hebrew, and Muslim societies.
May 2019 in “Ukraïnsʹkij bìofarmacevtičnij žurnal” This study observed that the cream-mask and gel-mask with Serenoa repens and Sophora japonica applied to a rat model of androgenic alopecia stimulated hair follicle growth similarly to a reference minoxidil treatment.
76 citations
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August 2018 in “International Journal of Cosmetic Science” This review discusses the use of Dermal Papilla cells as in vitro models for studying hair growth modulators, emphasizing their role in aiding the development of new hair treatments, but reports no new clinical results.
July 2020 in “Journal of the American Academy of Dermatology” This analysis found that spironolactone use is not associated with an increased risk of breast cancer recurrence in female survivors.
22 citations
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January 2018 in “Experimental Dermatology” This article reviews insights into the pathogenesis of primary cicatricial alopecias, such as lichen planopilaris, provided by emerging technologies, but it does not report new clinical results.
13 citations
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April 2016 in “Journal of Visualized Experiments” This study describes a method for isolating stem cells and keratinocytes from mouse hair follicles using FACS technology, facilitating the study of stem cell biology.
2 citations
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January 2009 in “Folia Pharmacologica Japonica” This review covers potential molecular targets for androgenetic alopecia treatments but presents no new experimental findings; the authors highlight various in vitro and in vivo screening methods for therapeutic compounds.
5 citations
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February 2011 in “Expert Opinion on Drug Discovery” This review discusses techniques and models for assessing hair growth activity but reports no new clinical findings, emphasizing the need for standardization and improved animal models.
11 citations
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December 2019 in “Dermatologic Therapy” This systematic review suggests that topical ketoconazole may improve hair regrowth and thickness in both animal and human studies for androgenetic alopecia, but further randomized controlled trials are needed.
This review examines the physiology of skin flap necrosis and various substances studied to improve flap viability, noting that promising results are mostly from animal studies, with nitroglycerin already tested in humans.
36 citations
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January 2015 in “Clinical and Translational Allergy” This review discusses allergic reactions to pollen in dogs, cats, and horses and suggests that these animals' spontaneous allergies could serve as models for translational clinical studies applicable to human allergies.
December 2024 in “Planta Medica” This systematic scoping review synthesized evidence from 175 in vivo studies on the effects of plant-based substances on hair growth, using animal models such as mice and rabbits. The authors created a checklist to improve data comparison and reproducibility in future hair growth research.
119 citations
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July 2016 in “Annals of the New York Academy of Sciences” This review examines the impact of vitamin D signaling in extraskeletal tissues and notes that expected benefits from animal and cell studies have not been consistently replicated in human clinical trials.
33 citations
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September 1961 in “Archives of Dermatology” This letter clarifies that colchicine induces anagen hair loss, as shown in animal studies, and corrects a misquotation by Kligman, who suggested it caused telogen effluvium.
June 2010 in “Journal of Cosmetic Dermatology” This article reviews the concept of caloric restriction and its potential anti-aging effects, highlighting animal studies and a human experiment in Biosphere II, but notes significant challenges for its application in humans.
13 citations
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January 1953 in “Archives of Dermatology” This research article discusses unsaturated compounds causing temporary hair loss in lab animals and reports no new results; previous studies indicated similar effects in humans.
September 2023 in “Curēus” This source discusses the complexity of cancer research, emphasizing that despite extensive studies, a comprehensive understanding of metastatic progression and therapeutic development remains elusive, and underscores the importance of animal models in breast cancer research.
110 citations
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February 2024 in “Journal of Chemical Information and Modeling” This study describes the PandaOmics platform, which uses AI and bioinformatics to identify new therapeutic targets and biomarkers for various diseases, demonstrating validation in laboratory and animal studies.
72 citations
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November 2020 in “Frontiers in Pharmacology” This review highlights potential benefits of jujube fruits on blood health, suggesting they might aid anemia prevention or treatment by supporting erythropoiesis and immune regulation, based on evidence from cell and animal studies.
27 citations
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April 2023 in “Pharmaceuticals” In this review, Ziziphus lotus was reported to have multiple traditional uses and demonstrated various pharmacological properties in lab and animal studies, with over 181 identified bioactive compounds; however, clinical trials are needed to confirm its efficacy as a medicinal agent.
12 citations
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March 2022 in “Development” This review outlines the role of mechanical forces in the development of sensory organs like eyes and ears, emphasizing insights from recent animal studies and microfabricated organoid systems; it presents no new experimental results.
4 citations
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July 2001 in “Journal of Cutaneous Medicine and Surgery” This study suggests that oral and topical tacrolimus may effectively treat psoriasis, atopic dermatitis, and hair growth disorders, although results are mostly based on small or animal studies.
1 citations
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January 2021 This source reports that platelet-rich plasma may be as effective as intralesional corticosteroids for treating patchy alopecia areata, with potential for earlier and more sustained results, while promising in vitro and animal studies on stem cells highlight the need for more clinical research.
July 2025 in “American Journal on Addictions” This study suggests that using opioids along with 5αRI may reduce opioid use disorder risk in humans, supporting similar findings from animal studies.
March 2025 in “International Journal For Multidisciplinary Research” This study reported that silver nanoparticles biosynthesized from the Dracaena trifasciata plant showed strong antioxidant properties but no anti-inflammatory action in vitro, suggesting these findings may warrant further in vivo animal studies.
May 2024 in “Journal of colloid and interface science” This study developed a bilayer bionic skin scaffold that mimics the skin's structure to resist microbial invasion and enhance wound healing, with in vivo animal studies showing improved collagen deposition, neovascularization, and hair follicle formation.
January 2024 in “Wiadomości Lekarskie” This research discusses the author's findings on methods for harvesting and preparing fat tissue for transplantation, highlighting rare but serious complications reported in animal studies and the use of conditioning devices.