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Hair loss is mainly caused by hormones, autoimmune issues, and chemotherapy, and needs more research for treatments.

Using rodents for research shows that health problems in the womb can cause diseases later in life.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Mice are useful for researching human hair loss and testing treatments, despite some differences between species.

The conclusion is that small hair follicles cause baldness in macaques, and treatments like antiandrogens and minoxidil can prevent hair loss and promote regrowth.

Erbium glass laser treatment may help with skin remodeling, reduce inflammation, and improve skin cell maturation.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Both mouse and rat models are effective for testing alopecia areata treatments.

The mouse models are effective for testing new hair loss treatments.

Cyclosporin is effective for treating skin conditions in small animals, but requires careful dosing and monitoring for side effects.

The flap assay grows the most natural hair but takes the longest, the chamber assay is hard work but gives dense, normal hair, and the patch assay is quick but creates poorly oriented hair with some issues.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.

Old treatments for other skin conditions showed promise for hair regrowth in mice with a hair loss condition.

3D cell-derived matrices improve tissue regeneration and disease modeling.

The study found that injecting spores directly into rabbit skin effectively caused fungal skin infections, with symptoms worsening over time.

A woman was injured by a hedgehog falling on her, causing skin lesions but no disease.

Cyclooxygenase-2 overexpression in mice skin causes hair loss like human androgenetic alopecia.

Stress worsens Tourette symptoms by increasing allopregnanolone levels.

Estazolam reduces anxiety-like behavior in PTSD by increasing allopregnanolone levels.

Topical diphencyprone helped regrow hair in mice and rats with a condition similar to human hair loss.

Cernitin™, a pollen extract, was found to significantly reduce pain and inflammation in rats with chronic prostatitis, suggesting it could be a useful alternative to certain anti-inflammatory drugs.

Canine epidermal neural crest stem cells could be a promising treatment for spinal cord injuries in dogs.

Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

Created microspheres show potential for safe and effective use in prostate artery embolization.

Finasteride raises suicide-linked aggression and stops clozapine's positive effects in schizophrenia animals.

Nebivolol cream may be a promising hair loss treatment by improving blood flow and nourishing hair follicles.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

The humanized AA mouse model is better for testing new alopecia areata treatments.

Trichloroethylene causes skin inflammation in mice by increasing certain immune proteins.