18 citations
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October 2021 in “Journal of Advanced Research” This study demonstrated that a new biomimetic tissue engineering strategy using DP spheroids with vascularization significantly restored the hair-inducing properties of dermal papilla cells compared to traditional 3D cultures.
18 citations
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March 2014 in “Drug Development and Industrial Pharmacy” This study evaluated new aqueous gel formulations of minoxidil without irritants and found that the calcium alginate gel showed the best performance in terms of drug release and skin permeation.
15 citations
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March 2021 in “Journal of Nanobiotechnology” This study developed a nanoscale biomimetic matrix that effectively and stably expands human hair follicle stem cells, offering a new tool for hair follicle reconstruction research.
13 citations
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January 2020 in “Scientific Reports” This study found distinct differences in protein expression and wound healing pathways between Acomys cahirinus and Mus musculus, highlighting potential targets for reducing fibrotic response in mammals.
12 citations
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June 2023 in “International Journal of Molecular Sciences” This review examines the potential of biomaterial-based wound dressings in managing diabetic foot ulcers, highlighting their versatility and therapeutic properties for promoting wound healing in individuals with diabetes mellitus.
10 citations
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November 2015 in “Elsevier eBooks” This review outlines the development and functional requirements of modern wound dressing materials and describes preparation methods and product performance, but reports no new clinical findings.
6 citations
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December 2024 in “International Journal of Biological Macromolecules” This study introduced a novel exosome-loaded sprayable hydrogel (ADA-aPF127@LL18/Exo) that significantly enhanced wound healing in a deep partial thickness burn model, showing improved antibacterial efficacy and promoting tissue recovery processes like epithelialization and hair follicle regeneration.
2 citations
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June 2023 in “Pharmaceutics” This study systematically reviews the development and applications of drug-loaded nanofiber scaffolds in wound healing, highlighting challenges such as maintaining drug activity and achieving controlled release, while summarizing preparation methods and describing advanced drug delivery schemes.
1 citations
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February 2024 in “Journal of nanobiotechnology” This review explores how combining extracellular vesicles with hydrogels and utilizing 3D bioprinting technologies creates innovative composite systems for wound healing, offering advanced mechanical and biological support, while addressing challenges like degradation and regulatory issues in clinical applications.
1 citations
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January 2024 in “Journal of Food Processing and Preservation” This study found that adding microcapsulated pumpkin seed protein hydrolysate to aloe vera drinks improved antioxidant activity, taste, and shelf life, with chitosan-alginate microcapsules effectively inhibiting microbial growth during 30 days of refrigerated storage.
July 2026 in “npj Regenerative Medicine” This study found that applying Laponite clay gels to skin wounds in mice did not speed up wound closure but significantly improved healing quality compared to phosphate-buffered saline or alginate treatments, with benefits such as enhanced re-epithelialization and hair follicle stimulation near wounds.
February 2025 in “International Journal of Bioprinting” This study constructed a 3D-printed scaffold using sodium alginate, gelatin, and alginate lyase hydrogel, which supports hair follicle regeneration in artificial skin, suggesting a promising strategy for tissue-engineered skin with functional appendages.
January 2024 in “Journal of chemical health risks” In this study, a multifunctional aloin-arginine-alginate bio-patch was developed, which transforms into a hydrogel to accelerate wound healing and offers antibacterial and anti-inflammatory benefits, making it promising for use in cutaneous regeneration.
September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, freezing gamma-irradiated amniotic fluid increased hair follicles and accelerated the transition to the anagen stage in rats, suggesting potential for treating hair loss safely and effectively.
July 2022 in “Journal of Investigative Dermatology” Arg1+ macrophages may play a role in Alopecia Areata, offering new treatment targets.
April 2021 in “Journal of Investigative Dermatology” Arg1+ macrophages may play a role in causing alopecia areata.
January 2008 in “Journal of Practical Medical Techniques” This study found that microencapsulated dermal papillae cells induced hair follicle regeneration in rat ears, differing from normal follicles in configuration, size, number, and differentiation degree.
March 2006 in “Chinese journal of plastic surgery” This study found that microencapsulated dermal papilla cells implanted into mice ears led to the successful regeneration of hair follicles, with APA microencapsulations of 400µm diameter allowing effective nutrient exchange.
January 2006 in “Chinese Journal of Medical Aesthetics and Cosmetology” This study found that microencapsulated human hair dermal papilla cells successfully induced hair follicle regeneration on the dorsal skin of nude mice, unlike control groups with free cells or empty microcapsules.
46 citations
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January 2020 in “Theranostics” This study demonstrated that OSA hydrogels enhanced the stability and retention of dermal papilla-derived extracellular vesicles, which significantly improved hair regeneration in both cultured human hair and a mouse depilation model.
15 citations
,
June 2020 in “Applied Materials Today” This study found that SA-MS hydrogel released Mo4+ ions which promoted healing of disease-impaired wounds by enhancing cell proliferation and angiogenesis, and through its photothermal effects addressed skin cancer-impaired wounds in mice.
1 citations
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July 2019 in “Farmatsevtychnyĭ zhurnal” This study developed an optimal gel-mask composition with nettle juice intended for treating telogen effluvium, determining the ideal concentrations for antioxidants and preservatives through extensive rheological and microbiological testing.
1 citations
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December 2016 in “Vìsnik farmacìï” This study found that a gel base with 0.2% potassium sorbate, 5% glycerin, and other specified components has optimal properties for use in telogen effluvium treatments.
1 citations
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June 2014 in “Vìsnik farmacìï” This study developed an emulsion formulation with optimal properties for androgenetic alopecia treatment using saw palmetto and Japanese Sophora extracts, evaluated for stability and release of active ingredients.
1 citations
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December 2010 in “Elsevier eBooks” This review covers cell transplantation methods for genitourinary reconstruction, discussing tissue sources and complications but presenting no new clinical findings.
July 2026 in “International Journal of Pharmaceutics X” In this study, researchers developed a biopolymer-based dual-layer wound dressing that significantly improved healing outcomes in a 14-day rat model, reporting 94% wound closure by day 15 and enhanced tissue regeneration, swelling properties, and cell viability.
May 2026 in “International Journal of Biological Macromolecules” In this study, researchers developed a biomacromolecular hydrogel to deliver plant-derived extracellular vesicles for treating androgenetic alopecia in a mouse model, which significantly improved hair regrowth and follicle density by activating Wnt/β-catenin signaling.
March 2026 in “Chemical Engineering Journal” The hydrogel helps heal diabetic wounds by combining antibacterial, antioxidant, and immune-boosting effects.
January 2026 in “Biomacromolecules” This study reports that a novel nanolipogel with moderate rigidity (NLG-2.5) enhances transdermal delivery of fucosterol, displaying superior permeability, targeting hair follicles, and promoting hair growth in androgenetic alopecia model mice by inhibiting inflammation and androgen pathways and promoting angiogenesis.
August 2025 in “Biomacromolecules” This study presents a novel composite hydrogel dressing with berberine-loaded silk fibroin microspheres and Calotropis gigantea fibers, demonstrating enhanced antibacterial activity, mechanical strength, and wound healing capabilities in treating chronic and infected wounds.