May 2025 in “The Journal of Rheumatology” In this case report, two patients with polyautoimmunity and difficult-to-treat lupus erythematosus experienced significant symptom improvement after adding anifrolumab to their regimen, suggesting its potential as an effective add-on therapy for refractory cutaneous symptoms in autoimmune conditions characterized by elevated interferon alpha activity.
March 2023 in “Scientific reports” This study presents evidence that hair matrix progenitors and the enzyme Stearoyl CoA Desaturase 1 may play a role in maintaining the dermal papilla niche via autocrine Wnt and paracrine Hedgehog signaling in mice.
May 2026 in “Journal of Cosmetic Dermatology” This meta-analysis found that fractional laser therapy significantly improved hair density in patients with androgenetic alopecia and exhibited a favorable safety profile, with mild to moderate adverse events. Combination therapy with laser and other treatments was more effective than other treatments alone.
2 citations
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November 2025 in “Biomedicines” This review explores how platelet- and marrow-derived biologics like PRP and BMAC exhibit both regenerative and antimicrobial properties useful in musculoskeletal conditions and wound healing, though their clinical outcomes are affected by preparation inconsistencies and lack of standardized protocols.
March 2024 in “Research Square (Research Square)” In this study, scalp cooling therapy was found to be well tolerated and effective at improving hair preservation for Asian women with breast or gynecological cancers undergoing certain chemotherapy regimens, particularly weekly paclitaxel, compared to historical controls.
August 2025 in “DS Reviews of Research in Life Sciences” In this study, women with polycystic ovary syndrome showed significantly higher levels of DHEA, IL-6, and TNF-α compared to healthy controls, indicating a possible link between these biomarkers and PCOS.
70 citations
,
August 1995 in “Fertility and Sterility” In this study, women with idiopathic hirsutism who took finasteride for 9 months experienced a significant reduction in hirsutism scores compared to those receiving a placebo, with minimal side effects.
150 citations
,
June 2014 in “Biomaterials” This study found that 'smart' peptide hydrogels improved wound healing in a rat model of partial thickness burns, achieving greater wound closure and faster debridement compared to a standard treatment.
2 citations
,
August 2023 in “Marine drugs” In this study, fish-derived collagen hydrolysate from tilapia scales improved hair growth and skin health in both cellular and mouse models, reducing oxidative stress and inflammation while enhancing hair quality and promoting beneficial gene expression.
October 2022 in “International Journal of Molecular Sciences” This study found that collagen peptides from Mozambique tilapia significantly promoted hair regrowth and increased the proliferation of hair growth factors in vitro and in vivo, suggesting potential as supplements for hair loss prevention.
64 citations
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June 2010 in “Journal of The European Academy of Dermatology and Venereology” This study suggests that 5 mg/day oral finasteride may increase hair density and thickness in normoandrogenic Asian women with female pattern hair loss over 12 months.
November 2025 in “Journal of Microbiology and Biotechnology” This study demonstrates that pea sprout extract promotes hair growth by activating specific signaling pathways and providing antioxidant and anti-inflammatory effects, suggesting its potential as a natural alopecia treatment.
32 citations
,
July 1999 in “Fertility and Sterility” This study found that both finasteride and flutamide effectively reduced hirsutism, with flutamide being more effective than finasteride in decreasing hirsutism scores and hair diameter over 12 months.
45 citations
,
July 2022 in “Frontiers in Pharmacology” This review discusses the mechanisms and targets of natural products for treating nonhealing wounds and reports no new experimental results, highlighting potential pathways and cytokines involved.
10 citations
,
August 2022 in “International Journal of Molecular Sciences” This review discusses mechanisms of wound healing impairment in leptin-deficient murine models used for diabetic research, and reports no new clinical results; the authors emphasize the need for further study.
February 2024 in “Journal of Cellular and Molecular Medicine” In this study using rat models, researchers developed a Pluronic@F-127 hydrogel to deliver the flavonoid pectolinarin, finding it accelerates wound healing and reduces scar formation by enhancing cell migration, proliferation, and antioxidant activity.
36 citations
,
August 2022 in “Molecular Therapy — Nucleic Acids” This review discusses various gene therapy and non-viral delivery methods to promote angiogenesis for chronic wound healing, but it reports no new clinical results.
18 citations
,
July 2022 in “Frontiers in Immunology” This review discusses the potential impact of volatile organic compound exposure on the onset and progression of autoimmune diseases and reports no new experimental findings.
14 citations
,
January 2015 in “Clinical Nutrition Research” This clinical trial found that the extract complex of Cistanche tubulosa and Laminaria japonica (MK-R7) significantly improved hair density and diameter in patients with patterned hair loss over 16 weeks.
8 citations
,
June 2021 in “Frontiers in Bioengineering and Biotechnology” This study investigated the effects of the 60% alcohol extract from Alnus sibirica and its active compound, oregonin, on hair health, observing anti-oxidative and anti-apoptotic benefits in human hair dermal papilla cells exposed to oxidative stress, suggesting potential as natural materials for hair loss prevention.
7 citations
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March 2021 in “Evidence-based Complementary and Alternative Medicine” This study found that Nelumbinis Semen extract may promote hair growth and reduce hair loss by increasing VEGF and IGF-1 expression and decreasing TGF-β1 in human dermal papilla cells and mice.
1 citations
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September 2021 in “Advances in skin & wound care” This review discusses possible mechanisms of SARS-CoV-2 transmission through the skin and sweat and reports no new clinical results, calling for further research on this potential route of infection.
February 2023 in “Vaccines” This review discusses the potential impact of COVID-19 on the male reproductive system and highlights unanswered questions regarding its mechanisms and implications for men's health and fertility, reporting no new clinical results.
April 2019 in “Archives of aesthetic plastic surgery” This study evaluated an 808-nm diode laser at different fluences for permanent axillary hair removal in Korean women and found that high-fluence treatment (14 J/cm2) effectively reduced hair density and thickness, with no significant difference in comfort compared to lower fluences.
2 citations
,
August 2014 in “PubMed” This case report details a woman with postural orthostatic tachycardia syndrome who experienced notable dermatological symptoms, including evanescent hyperemia, which improved with the use of an oral angiotensin II type 1 receptor antagonist.
June 2025 in “Microorganisms” In this study, researchers observed significant differences in hair follicle microbiome diversity and microbial composition between hair loss and healthy groups, uncovering specific patterns and functional changes associated with female pattern hair loss, which may aid future targeted approaches for androgenetic alopecia.
18 citations
,
March 2008 in “British Journal of Dermatology” This study found that finasteride 1 mg daily decreased 5alpha-dihydrotestosterone levels and improved hair growth in younger men with androgenetic alopecia, with higher initial hormone levels predicting better response.
5 citations
,
October 2014 in “Gynecological Endocrinology” This case study describes a 15-year-old girl with a Sertoli–Leydig cell tumor who showed high androgen levels and steroidogenic responses similar to patients with polycystic ovary syndrome before surgery.
38 citations
,
September 2021 in “Signal Transduction and Targeted Therapy” This review discusses genetic factors contributing to susceptibility and outcomes in COVID-19, including ACE, ACE2, TMPRSS2 variants, HLA genotype, and ABO blood group, but reports no new experimental results.
November 2023 in “Klìtinna ta organna transplantologìâ” This study reviews the regenerative potential and clinical applications of exosomes derived from mesenchymal stem cells in conditions like COVID-19, alopecia, skin aging, and osteoarthritis, highlighting their role as a promising tool in regenerative medicine.