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Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Lean and obese women with PCOS have similar levels of insulin resistance, indicating it's a core aspect of the condition.

Both birth control pills improved hormone levels and skin conditions in women with hyperandrogenism, but the one with drospirenone was more effective.

Cyproterone acetate is effective for treating hirsutism and acne in women by blocking androgens in the skin and also works as a contraceptive.

Managing emotional distress, obesity, insulin resistance, and high male hormones is crucial for improving well-being in women with PCOS.

Rare ovarian tumors can cause hyperandrogenism, even if imaging appears normal.

Women with PCOS have more depression and stress due to high androgen levels, not obesity or insulin resistance.

Men and women experience skin aging differently due to changes in sex hormone levels with age.

A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.

Cabergoline is more effective and has fewer side effects than bromocriptine for treating women with hyperprolactinemic amenorrhea.

Higher doses of oestradiol implants improve bone density in postmenopausal women.

Long-term use of oral contraceptives, especially starting before age 20, may increase the risk of early-onset breast cancer.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Finasteride safely reduces excessive hair growth in women.

A woman's rare adrenal tumor caused high testosterone and cortisol levels, which normalized after the tumor was removed.

Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.

Finasteride effectively lowers specific hormone levels, helping monitor treatment progress.

A postmenopausal woman's hirsutism and high testosterone levels improved after surgery for an ovarian tumor not seen on ultrasound.

Young women with nonclassic congenital adrenal hyperplasia may experience worse sexual function and mild depression compared to healthy women.

Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.

Testosterone replacement may help postmenopausal women with sexual function and bone density, but suitable treatments are limited.

Combining flutamide and finasteride can reduce prostate weight and tumor growth, potentially benefiting treatments needing optimal DHT inhibition.

Women with congenital adrenal hyperplasia (CAH) have more sexual function issues than those with polycystic ovary syndrome (PCOS), but physical activity can improve sexual functioning in all women.

Finasteride and metformin both help treat PCOS, but using them together works best.

Women with hyperandrogenism have higher androgen levels and lower SHBG, which may contribute to conditions like excessive hair growth and early puberty.

Testosterone replacement can help menopausal women with various symptoms, but should be used carefully and is not yet officially licensed in the UK for women.

Clinical signs of excess male hormones and actual hormone levels in the blood do not always match in women with polycystic ovary syndrome.

Ovarian Hyperthecosis caused hypersexuality in an older woman and was successfully treated with surgery.

Taking biotin can lead to incorrect low results in free testosterone tests.