Search

everythinglearnresearchcommunity

for

Search:↓

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.

Testosterone with or without finasteride doesn't improve thinking skills in older men with low testosterone.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

New genes and pathways are important for testosterone production and male sexual development.

Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Hidradenitis suppurativa improves with antiandrogen therapy.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.