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Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.

Muscles can make their own androgens, which may help muscle growth.

Genetic variations greatly affect individual metabolism and can impact health and disease risk.

Neuroactive steroids and the enzyme 5α-reductase might be involved in the development of Tourette's syndrome.

δ-GABAA receptors affect alcohol consumption based on the estrous cycle and influence movement regardless of the cycle.

Gut microbes significantly affect brain steroid levels.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Finasteride reduces opioid use and withdrawal symptoms in animals.

The main prostate diseases in dogs are benign growth, infections, and cancer, with various treatments ranging from drugs to surgery, but cancer treatments have limited success.

The conclusion is that new plant-based treatments for hair loss may work by targeting certain enzymes.

The skin acts like an endocrine organ, producing hormones that affect various body functions and skin health, and understanding this can lead to new treatments.

Men and women react differently to opioids, with hormones potentially influencing these differences.

Ferulic acid may help control menstrual cycle-related epilepsy by affecting female hormones.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

A new method accurately measures steroid hormones in a few hair strands and could help study chronic stress and hair loss.

Hirsutism is common body hair growth due to genetics and hormones, and while not a disease, it can be distressing; virilisation includes hirsutism with other male traits and needs medical attention.

Testosterone replacement may help postmenopausal women with sexual function and bone density, but suitable treatments are limited.

Finasteride blocks progesterone production in specific tumor cells, potentially causing side effects.

Some women with excess hair growth have a hormone condition that can't be diagnosed by blood or urine tests alone.

Women with effluvium have higher levels of certain urinary steroids, possibly due to stress and increased adrenal activity.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Androgens can both increase and decrease hair growth in different parts of the body.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.