research Investigation of Hub Genes and Immune Infiltration in Androgenetic Alopecia Using Bioinformatics Analysis
Immune activities and specific genes are important in male pattern baldness.
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research Drug Repositioning Using In Silico Compound Profiling
Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.
research In Vivo and In Vitro Exposure to Free Fatty Acids Induce Increased Androgen Production in Animal Models: A Potential Pathogenic Factor of Polycystic Ovary Syndrome
Free fatty acids may increase androgen production, potentially contributing to polycystic ovary syndrome.
research Fulvestrant: A New Treatment Option for Advanced Breast Cancer - Tolerability Versus Existing Agents
Fulvestrant is a well-tolerated new treatment for advanced breast cancer that may delay chemotherapy.
research Unlocking the Power of Light on the Skin: A Comprehensive Review on Photobiomodulation
Light-based treatment, Photobiomodulation, shows promise for non-invasive skin therapy with few side effects.
research Clinical Efficacy and Safety of Low-Dose Flutamide Alone and Combined with an Oral Contraceptive for the Treatment of Idiopathic Hirsutism
Low-dose flutamide helps reduce excessive hair growth and is even more effective with birth control, without bad effects on blood fats.
research Safety of Testosterone Use in Women
Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.
research Pharmacology of Different Progestogens: The Special Case of Drospirenone
Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.
research Alopecia Management Potential of Rosemary-Based Nanoemulgel Loaded with Metformin: Approach Combining Active Essential Oil and Repurposed Drug
Rosemary-based gel with metformin may effectively treat hair loss like minoxidil.
research Formulation and Evaluation of Valproic Acid Microemulsions for Enhanced Transfollicular Delivery in Guinea Pig Skin
Valproic acid microemulsions improve skin delivery compared to regular solutions.
research Repurposed Drugs: Current Trends In Drug Discovery
Drug repurposing speeds up development, cuts costs, and uses known safe drugs, but faces challenges like regulations and patents.
research Assessing Medication Use Patterns Among Patients With Polycystic Ovary Syndrome at a Tertiary Care Teaching Hospital in South Korea: A Retrospective Study
Most patients with PCOS were prescribed medroxyprogesterone acetate or oral contraceptives, with some experiencing side effects or needing prescription changes.
research Health Benefits, Antioxidant Activity, and Sensory Attributes of Selected Cold-Pressed Oils
Cold-pressed rapeseed oil is most resistant to oxidation and certain oils may reduce chronic disease risk; consumers like the taste of pumpkin oil best.
research Successful Treatment of Female-Pattern Hair Loss with Spironolactone in a 9-Year-Old Girl
Spironolactone successfully treated hair loss in a 9-year-old girl.
research Pediatric Androgenetic Alopecia: A Retrospective Review of Clinical Characteristics, Hormonal Assays, and Metabolic Syndrome Risk Factors in 23 Patients
Androgenetic alopecia in teens is linked to obesity and other metabolic risks, needing early diagnosis and management.
research A Study on the Clinical, Biochemical, and Hormonal Profile of Polycystic Ovary Syndrome Patients Attending a Tertiary Care Hospital
The study concluded that a higher waist-hip ratio significantly increases the risk of metabolic syndrome in women with PCOS.
research Behavior of the Two Circulating Androgens Testosterone and DHEA and Their Main Intracellular Metabolites in an Androgen-Sensitive Sebocyte Cell Line
Testosterone affects androgen receptors and lipid storage in cells, while DHEA does not convert to testosterone or affect these receptors in the same way.
research Facial Hair Enhancement With Minoxidil—An Off-Label Use
Minoxidil can help increase facial hair growth.
research Does PSADT After Radical Prostatectomy Predict Overall Survival?—A Report from the SEARCH Database Group
Shorter PSADT after prostate surgery is linked to higher risk of death.
research Polycystic Ovarian Syndrome in Patients with Schizophrenia Treated with Atypical Antipsychotics: A Case Control Study
Women with schizophrenia on atypical antipsychotics are more likely to have polycystic ovarian syndrome (PCOS) than women without schizophrenia.
research Topical Solutions for Androgenetic Alopecia: Evaluating Efficacy and Safety
Topical treatments for hair loss can be effective but need careful safety evaluation.
research Optimal Stimulation Toward the Dermal Papilla Lineage Can Be Promoted by Combined Use of Osteogenic and Adipogenic Inducers
Combining specific inducers helps dermal papilla cells regain hair-forming ability.
research The Effect of Alfacalcidiol and Metformin on Metabolic Disturbances in Women with Polycystic Ovary Syndrome
Metformin effectively improves metabolic symptoms in women with PCOS, while alfacalcidiol does not have a significant impact.
research Unconventional Side Effects of Antidepressants: Focus on Emotional Blunting
Some antidepressants can cause emotional numbness and other unusual side effects.
research Hyperandrogenemia in Women with Polycystic Ovary Syndrome: Prevalence, Characteristics, and Association with Body Mass Index
High levels of male hormones are very common in women with PCOS and affect their metabolism differently depending on their weight.
research Treatment Patterns and Unmet Needs in the Management of Alopecia Areata: Results of a Physician’s Survey in the Middle East
Doctors in the Middle East need better treatments and more knowledge about new therapies for hair loss condition Alopecia Areata.
research Endocrinological Assessment in Transgender Individuals
The document concludes that personalized hormonal treatments are important for transgender individuals and more research is needed for non-binary treatments.
research Targeting Neurosteroid Synthesis as a Therapy for Schizophrenia-Related Alterations Induced by Early Psychosocial Stress
A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.
research Diagnosis of an Indistinct Leydig Cell Tumor by Positron Emission Tomography-Computed Tomography
A PET-CT scan successfully located a hard-to-find Leydig cell tumor in a woman with hormonal symptoms.
research Disease Burden, Clinical Management, and Unmet Treatment Need of Patients With Moderate to Severe Alopecia Areata: Consensus Statements, Insights, and Practices From CERTAAE Delphi Panel
Alopecia Areata significantly lowers quality of life and current treatments are inadequate, highlighting a need for better therapies and standardized treatment protocols.