33 citations
,
January 2013 in “Dermatology” This study found that among women above 15 years with acne, 54.56% exhibited hyperandrogenism, with dehydroepiandrosterone sulfate levels most frequently elevated.
January 2016 in “Journal of SAFOG” This study observed that androgenic hormone levels were higher in high school girls with PCOS phenotypes accompanied by menstrual disorders, particularly oligomenorrhea.
March 2025 in “Archives of Dermatological Research” Early-onset hair loss in Egyptian males is linked to genetics, hormones, and lifestyle factors like smoking and diet.
March 2017 in “Journal of Dermatology” This article is a letter discussing variations in male sex hormone levels among different pattern subtypes of androgenetic alopecia and does not present new research results.
57 citations
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November 2006 in “International Journal of Cancer” This study found that the SRD5A2 A49T A variant is associated with an increased risk of prostate cancer, lower circulating 3α‐diolG levels, and a decreased risk of baldness.
36 citations
,
April 2011 in “Journal of The American Academy of Dermatology” People with hair loss have higher risk of high blood sugar and diabetes, and lower levels of a specific hormone.
23 citations
,
December 2004 in “Differentiation” This article reviews the interaction between sex hormone pathways and morphogenesis-related signaling in epithelial organ development, using a chicken model to propose testable hypotheses, but reports no new clinical results.
15 citations
,
June 2020 in “Experimental Dermatology” This review discusses recent genetic findings on hormonal signaling pathways in androgenetic alopecia, reporting no new study results but highlighting the need for further investigation.
9 citations
,
October 2018 in “Medical Science Monitor” In this study, oral finasteride therapy was associated with decreased DHT levels and improved hair loss severity in young male AGA patients, while hormonal changes influenced the curative effect.
February 2024 in “Malahayati Nursing Journal” This study found that hirsutism in women is associated with elevated androgen hormone levels and increased serum TNFα, suggesting a link between androgen-driven inflammatory responses and excessive hair growth.
June 2013 in “Vestnik dermatologii i venerologii” This study found that women with androgenic alopecia often have increased dihydrotestosterone levels, suggesting potentially enhanced activity of 5-alpha-reductase, with the saliva free testosterone level providing valuable hormonal background information.
December 2015 in “Vestnik dermatologii i venerologii” This article reviews studies on androgen hormone profiles in men with androgenetic alopecia and the effects of androgens and 5-alpha reductase on hair follicles, but provides no new findings.
January 2008 in “The Year book of endocrinology” Gene variant linked to prostate cancer, hormone levels, and hair loss.
August 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)” This article reviews research on androgen hormone levels in males with androgenetic alopecia and explores the effects of androgens on hair follicles, but it reports no new findings.
13 citations
,
September 1986 in “Archives of Dermatology” This study found that women with female pattern baldness often had a higher ratio of 3 alpha,17 beta-androstanediol glucuronide to sex hormone-binding globulin and lower serum sex hormone-binding globulin, possibly indicating minimal androgen excess.
November 1986 in “PubMed” In this study, women with male pattern alopecia had significantly lower serum sex hormone binding globulin levels compared to healthy controls, while testosterone levels remained similar.
January 2025 in “Indian Journal of Animal Research” This study observed that herbal feed supplementation in Frieswal breeding bulls improved semen volume and motility, while significantly lowering dihydrotestosterone levels, suggesting a potential mechanism for enhancing semen quality.
This study found that premenopausal exercising women with oligomenorrhea had lower triiodothyronine levels and truncal fat percentage compared to other groups, suggesting distinct energetic and reproductive profiles.
15 citations
,
August 2010 in “Fertility and sterility” This study found that girls with polycystic ovary syndrome and longer SHBG and AR gene repeats experienced greater improvements in lipid and androgen levels after one year of metformin treatment.
13 citations
,
May 1998 in “The Journal of Clinical Endocrinology & Metabolism” This study found that hCG decreased 5α-reductase and androgen receptor levels in skin samples from women in vitro, suggesting that human skin responds to LH/hCG treatment.
55 citations
,
July 1997 in “Clinical Endocrinology” This study found that administering growth hormone to adult men with GH deficiency increased their sexual hair scores, suggesting an auxiliary effect on androgen action in the skin.
29 citations
,
September 1983 in “British Journal of Dermatology” This study found that men with androgenetic alopecia had significantly lower levels of sex hormone binding globulin and higher salivary testosterone compared to controls, while plasma testosterone levels did not differ.
3 citations
,
February 2021 in “JAMA Dermatology” Masculinizing hormone therapy increases the risk of hair loss in transgender and gender-diverse patients.
September 1989 in “PubMed” This study found no significant differences in sex-hormone binding globulin and androgen serum levels between women with stage II androgenetic alopecia and controls, suggesting that genetically-determined androgen sensitivity might play a major role in the condition.
April 2021 in “Journal of Investigative Dermatology” This study found that transgender patients on masculinizing hormone therapy had a higher likelihood of developing acne compared to cisgender women, and were more likely to experience AGA compared to cisgender women.
August 1987 in “European journal of endocrinology” This study found no correlation between plasma androgen levels and androgenetic alopecia in women, suggesting that increased androgen action may not be reflected in these parameters.
46 citations
,
June 1983 in “Cleveland Clinic Journal of Medicine” In this study, women with diffuse alopecia were found to have higher serum levels of adrenal androgen DHEAS, which may contribute to disrupted scalp hair growth.
10 citations
,
February 2020 in “Endocrine” This study found that finasteride treatment in males with androgenetic alopecia was linked to significant changes in sperm parameters and increased testosterone levels, but no sexual dysfunction was observed, and sperm parameters returned to baseline after treatment stopped.
5 citations
,
January 2021 in “Biomedicine & Pharmacotherapy” This study suggests that policosanol may prevent androgenetic alopecia in mice by regulating hormone levels and suppressing premature hair follicle entry into the regression phase.
September 2023 in “Clinical, Cosmetic and Investigational Dermatology” This study found a significant negative correlation between serum SHBG levels and androgenetic alopecia severity in women, but not in men, while no significant correlation was observed for testosterone, estradiol, dehydroepiandrosterone sulfate, and vitamin D levels with hair loss severity across genders.