1 citations
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February 2024 in “Pharmacognosy Journal” In this study, fenugreek seed extract showed significant androgenic and spermatogenic effects in male rats, likely through inhibiting testosterone metabolism, without impacting cardiovascular health.
10 citations
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August 2020 in “Dermatologic Therapy” This study found that platelet-rich plasma significantly increased hair diameter in both men and women with androgenetic alopecia but improved hair density only in men.
5 citations
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February 2013 in “Dermatology and therapy” This study found that applying Crescina® HFSC lotion for four months effectively increased hair growth and reduced hair loss in males with androgenetic alopecia.
2 citations
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March 2015 in “World journal of acupuncture-moxibustion” This study concluded that catgut embedment combined with moxibustion and bloodletting may be more effective than finasteride for treating androgenic alopecia, possibly due to reductions in testosterone and the testosterone/estradiol ratio.
January 2025 in “Journal of Dermatological Treatment” This systematic review and meta-analysis found that adding low-level laser therapy to minoxidil treatment for androgenic alopecia does not significantly enhance hair count or diameter compared to using minoxidil alone.
August 2023 in “Journal of Cosmetic Dermatology” This study found that combining minoxidil and spironolactone was more effective for hair density and severity of hair loss in women with androgenic alopecia compared to minoxidil and finasteride, with no serious adverse effects reported.
January 2018 in “프로그램북(구 초록집)” This study found that applying adipocyte-derived stem cell conditioned media increased hair count significantly in androgenic alopecia patients compared to saline, suggesting it as a potential treatment, with no adverse effects reported.
January 2015 in “世界针灸杂志(英文版)” In this study, treating androgenic alopecia with catgut embedment, moxibustion, and bloodletting showed better results after 3 months than finasteride, potentially due to decreased testosterone levels and testosterone/estradiol ratios.
June 2026 in “International Journal of Current Pharmaceutical Review and Research” This study found that combining platelet-rich plasma with topical minoxidil improved hair density and patient satisfaction in androgenetic alopecia patients more than minoxidil alone, with no serious adverse events reported.
May 2026 in “Aesthetic Plastic Surgery” This study found that autologous growth factor injections for androgenetic alopecia improved hair density, thickness, and patient satisfaction over 12 months; however, high bias risk and non-standardized methods limit the evidence's reliability, highlighting the need for larger, standardized trials.
February 2026 in “Archives of Dermatological Research” In this study, microneedle-assisted delivery of polyglutamate significantly improved hair parameters, scalp symptoms, and quality of life in androgenetic alopecia patients, with no serious adverse reactions reported.
November 2025 in “Aesthetic Plastic Surgery” This meta-analysis found that while PRP therapy may result in higher patient satisfaction and better negative hair pull test results, it shows no clear advantage over minoxidil in terms of hair density or regrowth in androgenetic alopecia treatment.
September 2025 in “Frontiers in Medicine” This study assessed the effectiveness of various combinations of minoxidil with other agents for androgenetic alopecia, finding that platelet-rich plasma and basic fibroblast growth factor combined with minoxidil significantly increased hair density, while different combinations were optimal depending on gender.
August 2025 in “Lasers in Medical Science” In this study, the combination of low-level laser therapy and topical minoxidil was found to improve hair density and diameter more effectively than minoxidil alone in treating androgenic alopecia, with similar safety profiles observed in both groups.
July 2025 in “Colloids and Surfaces B Biointerfaces” This study found that the new delivery system HL@Mi enhanced the skin penetration, local bioavailability, and safety of minoxidil, supporting improved hair growth in an androgenetic alopecia animal model.
June 2025 in “International Journal of Research in Dermatology” In this case series, researchers observed that combining 0.1% tretinoin gel with 5% minoxidil over 90 days improved hair growth and patient satisfaction in androgenetic alopecia patients who did not previously respond to minoxidil alone, with significant increases in hair count, density, and quality.
April 2025 in “Journal of Pioneering Medical Science” This study concluded that oral and topical minoxidil have similar overall benefits in treating androgenetic alopecia, but topical minoxidil improved hair density more and had fewer adverse effects.
April 2025 in “Archives of Dermatological Research” In this study, microneedling-administered topical cetirizine was observed to significantly enhance hair density and increase vellus hair prevalence in men with androgenetic alopecia, with no notable adverse effects reported.
February 2025 in “Archives of Dermatological Research” This study found that combining microneedling with 5% Minoxidil and Finasteride significantly improved hair density and hair shaft diameter in males with androgenetic alopecia, outperforming Minoxidil alone or in combination with Finasteride, although changes in hormonal levels and trace elements were not significant.
December 2024 in “Archives of Clinical & Experimental Dermatology” This controlled study found that patients with androgenetic alopecia treated with a combination of subcutaneous adipose-derived mesenchymal stem cells and oral minoxidil showed significantly better hair growth outcomes than those treated with oral minoxidil alone, with improvements ranging from 25-40% versus 5-10% over six months.
November 2024 in “Journal of the American Academy of Dermatology” Combining PRP, microneedling, and minoxidil may improve hair regrowth in severe hair loss cases.
August 2024 in “Scholars Journal of Applied Medical Sciences” This study found that combining platelet-rich plasma therapy with minoxidil significantly improved hair growth and hair follicle cell proliferation in men with androgenetic alopecia compared to either treatment alone.
August 2024 in “Saudi Journal of Medical and Pharmaceutical Sciences” In this study, PRP combined with minoxidil was found to be more effective in improving hair counts in androgenetic alopecia patients compared to minoxidil alone or with dermaroller, showing significant improvements at both 3 and 5 months.
May 2024 in “Journal of drug delivery and therapeutics” This literature review suggests that platelet-rich plasma therapy shows promise for improving hair density and patient satisfaction in men with androgenetic alopecia, though standardized protocols are still needed.
March 2023 in “International Journal of Trichology” This study found that a combination of topical 5% minoxidil and 0.25% finasteride was more effective at improving hair density and satisfaction in men with androgenetic alopecia than either treatment alone over 24 weeks.
The systematic review and meta-analysis evaluated the efficacy and safety of combining microneedling therapy with other treatments for androgenic alopecia. The analysis included multiple randomized clinical trials, providing a comprehensive assessment of the combined treatment approach. The findings suggested that microneedling, when used in conjunction with other therapies, improved hair growth outcomes in patients with androgenic alopecia. The study also reported that the combined treatment was generally safe, with no significant adverse effects noted. However, as the review was completed but not published, the detailed results and specific number of participants involved in the trials were not disclosed.
March 2023 in “Clinical, Cosmetic and Investigational Dermatology” This study concluded that both oral and topical spironolactone effectively treat androgenetic alopecia, with topical administration being safer and suitable for any gender, especially when combined with minoxidil.
August 2021 in “International journal of advanced research” In this study, PRP therapy initially improved hair density in androgenetic alopecia, but effects decreased over time, suggesting additional treatment may be needed for sustained results.
August 2021 in “Zenodo (CERN European Organization for Nuclear Research)” This study observed that while platelet-rich plasma showed positive short-term effects on hair density in individuals with androgenic alopecia, its effectiveness declined after four months, suggesting possible need for additional treatment.
August 2020 in “Rossiiskii Zhurnal Kozhnykh i Venericheskikh Boleznei” This review analyzes platelet-rich plasma preparation methods for treating androgenetic alopecia but reports no new clinical results, suggesting a need for further research to evaluate efficacy and tolerance.