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Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.

The substance MK386 effectively blocked testosterone conversion and reduced cell growth in certain skin cells, but inhibiting 5α-reductase alone may not greatly improve acne.

5-Alpha Reductase Inhibitors are effective for male hair loss and some skin conditions, but their effectiveness in women and safety concerns require careful use.

Skin problems can be caused or worsened by physical forces and pressure on the skin.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Myo-inositol helps improve skin conditions and metabolic profiles in young women with PCOS.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

Finasteride in male rats causes liver and metabolic issues in their offspring.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

Activating NRF2 might help treat hair disorders by improving antioxidant defenses.

Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

The oral contraceptive ethinylestradiol/chlormadinone acetate is effective in reducing acne and improving other skin conditions related to high androgen levels.

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

Bee venom might be a good alternative treatment for various skin conditions because it has many healing properties.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

The document concludes that diagnosing and treating Congenital Adrenal Hyperplasia is complex and requires a team approach due to its effects on the skin and other symptoms.

Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Certain diets can affect skin conditions, but more research is needed to understand these relationships fully.

Beard cells, unlike scalp cells, produce growth factors in response to testosterone, which may explain differences in hair growth.