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The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

The study found no link between baldness patterns and androgen levels in men with benign prostate enlargement or prostate cancer.

Proxalutamide improved recovery, lowered death rates, and reduced hospital stay for COVID-19 patients.

Age, smoking, and lower BMI increase facial wrinkles; men wrinkle more than women, except in old age; pale skin and certain hormonal factors can protect against wrinkles.

Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

Prostate-specific antigen may be a new marker for excess male hormones in women with polycystic ovary syndrome.

Estrogens and progesterone are key in regulating melasma pigmentation.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

Treatment can improve survival and symptoms in dogs with Cushing's disease, but outcomes are unpredictable.

Bleaching hair damages protein structure, especially keratin, leading to weakened hair.

Balding hair follicle cells are smaller, grow less well, and need more effort to culture than non-balding cells.

Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.

The document explains that hirsutism, often caused by hormonal issues, can be managed with treatment to improve both physical appearance and mental health.

PSA levels could help detect illegal steroid use in female athletes but face challenges like cost and PCOS prevalence.

Levofloxacin may cause skin discoloration and hair loss as side effects.

Oxidative stress affects hair loss in men with androgenetic alopecia.

White wax and policosanol from white wax effectively reduced hair loss and promoted hair growth in mice better than a known hair growth drug.

Minoxidil use increases facial hair growth in females, more in older users.

The article explains how to identify and treat excessive hair growth in women, which can be distressing and may signal other health problems.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Nonobese, normotensive Indian women with PCOS may have a higher risk of heart problems linked to inflammation and insulin resistance.

Certain genetic variations in the RAB5B gene are linked to a higher risk of polycystic ovary syndrome in Chinese Han women.

The number of advanced breast cancer cases in women under 40 has increased, but the overall numbers are still low.

There is no gold standard treatment for hidradenitis suppurativa due to insufficient evidence.

AGA is a common hair loss disorder, and early diagnosis and treatment with minoxidil or finasteride can help reduce emotional distress.

Men and women experience skin aging differently due to changes in sex hormone levels with age.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Colorimetry can accurately measure hair growth rates in mice.