research Androgen Treatment in Women
Testosterone therapy can help with androgen deficiency in women but should be used with caution and monitoring due to potential risks.
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research Androgen Treatment in Women: A Review of Testosterone Therapy and Its Effects
Testosterone therapy can help improve sexual function, mood, and bone density in women with low androgen levels, but more research is needed on long-term safety.
research Biological Activity of Novel Progesterone Derivatives Having Bulky Ester Side Chains at C-3
The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.
research Development of a Liquid Chromatography/Mass Spectrometry-Based Inhibition Assay for Screening Steroid 5-Alpha Reductase in Human and Fish Cell Lines
A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.
research Comparative Study to Evaluate Tolerability of Topical 5% Minoxidil Novel Formulation and Alcohol-Based Conventional Solutions in Treatment of Androgenetic Alopecia in Indian Men: Randomized Double-Blind Study
New 5% minoxidil solution improves scalp hydration, reduces redness, and may be safer for sensitive users.
research A Review of Androgen-Progestin Regimens for Male Contraception
Hormonal male contraception is effective and could be market-ready, but more research is needed to ensure safety for all ethnic groups.
research Polycystic Ovary Syndrome: A Comprehensive Overview
The document concludes that effectively managing PCOS requires a multifaceted approach.
research Revised 2003 Consensus on Diagnostic Criteria and Long-Term Health Risks Related to Polycystic Ovary Syndrome (PCOS)
The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.
research Acne-Associated Syndromes: Models for Better Understanding of Acne Pathogenesis
The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.
research Inhibition of Skin 5α-Reductase by Oral Contraceptive Progestins In Vitro
Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.
research Clinical Features of Familial Lewy Body Parkinsonism Caused by α-Synuclein Triplication (Iowa Kindred) with Video Documentation
The document describes a woman with familial Parkinson's disease due to a genetic mutation, showing severe symptoms and poor response to treatment, and suggests finasteride may help reduce symptoms in Tourette syndrome.
research Sexual Problems of Men With Androgenic Alopecia Treated With 5-Alpha Reductase Inhibitors
Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.
research Evaluation of the 5α-Reductase Inhibitor Finasteride on Reproduction and Gonadal Development in Medaka, Oryzias Latipes
Finasteride negatively affects fish reproduction and gonadal development.
research Acne
Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.
research Increased Insulin Sensitivity by Metformin Enhances Intense-Pulsed-Light-Assisted Hair Removal in Patients with Polycystic Ovary Syndrome
Taking metformin with intense-pulsed-light therapy improves hair removal for people with PCOS.
research The Effect of Weight Loss and Treatment with Metformin on Serum Vaspin Levels in Women with Polycystic Ovary Syndrome
Weight loss and metformin don't significantly change vaspin levels in women with PCOS.
research Examining the Safety and Efficacy of Low-Level Laser Therapy for Male and Female Pattern Hair Loss: A Review of the Literature
Low-level laser therapy safely and effectively improves hair growth and coverage for male and female pattern hair loss.
research Colorimetry Provides a Rapid Objective Measurement of De Novo Hair Growth Rate in Mice
Colorimetry can accurately measure hair growth rates in mice.
research Insights From Liquid Chromatography-Mass Spectrometry-Measured Androgens in Indian Women With Polycystic Ovary Syndrome
Androstenedione is better than testosterone for diagnosing PCOS in Indian women.
research Quantification of Reproductive Hormones in Hair of Captive Adult Brown Bears and Their Application as Indicators of Sex and Reproductive State
Measuring reproductive hormones in brown bear hair could help identify their sex and reproductive state, but better collection methods or lab techniques are needed.
research Hair Removal Using a Long-Pulsed Alexandrite Laser
The long-pulsed alexandrite laser is effective for hair reduction, particularly for light-skinned individuals with dark hair, but caution is needed for darker skin.
research Pharmacological Inhibition of DGAT1 Induces Sebaceous Gland Atrophy in Mouse and Dog Skin While Overt Alopecia Is Restricted to the Mouse
Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.
research Lipid Nanoparticles for Topical and Transdermal Delivery of Pharmaceuticals and Cosmeceuticals
Lipid nanoparticles improve drug delivery through the skin, offering stability, controlled release, and better compatibility with skin.
research Sex Hormone-Binding Globulin as an Early Biomarker and Therapeutic Target in Polycystic Ovary Syndrome
SHBG may be a useful early indicator and treatment target for PCOS.
research Age-Dependent Endocrine Disorders Involved in the Pathogenesis of Refractory Acne in Women
Hormonal imbalances, often indicating conditions like PCOS, are common in women with hard-to-treat acne, and a treatment approach addressing these imbalances may be needed.
research Ovarian Hormones and Adrenal Androgens During a Woman's Life Span
Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.
research A Quantitative Ultra-Performance Liquid Chromatography High-Resolution Mass Spectrometry Analysis of Steroids from Human Scalp Hair
The method can measure multiple steroids in human hair to study long-term steroid metabolism, especially in newborns and children.
research LC-APCI+-MS/MS Method for the Analysis of Ten Hormones and Two Endocannabinoids in Plasma and Hair from Mice with Different Gut Microbiota
The method accurately measures hormones and endocannabinoids in mice, showing gut microbiota diversity affects these levels and may influence stress and reproductive systems.
research Female Doping: Observations From a Data Lake Study in the Hospital District of Helsinki and Uusimaa, Finland
Many women who have used performance-enhancing drugs in Finland show high rates of mental health and substance use issues, and most have normal red blood cell counts.
research Comparative Study Between Mesotherapy and Topical 5% Minoxidil by Dermoscopic Evaluation for Androgenic Alopecia in Males: A Randomized Controlled Trial
Mesotherapy is not significantly better than minoxidil for treating male hair loss.